• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=19378335).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Asp (c.734G>A); ClinVar=VCV000012355; Zygosity=Unspecified (PubMed=19378335).
  

PubMed=11606375
Amanda J. Philp, Ian G. Campbell, Christine Leet, Elizabeth Vincan, Steven P. Rockman, Robert H. Whitehead, Robert J.S. Thomas, Wayne A. Phillips;
The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.
Cancer Res. 61:7426-7429(2001)

PubMed=19378335; DOI=10.1002/ijc.24289
Hui-Hua Zhang, Francesca E. Walker, Sara Kiflemariam, Robert H. Whitehead, David Williams, Wayne A. Phillips, Thomas Mikeska, Alexander Dobrovic, Antony Wilks Burgess;
Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Int. J. Cancer 125:297-307(2009)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)