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Cellosaurus LIM2537 (CVCL_4441)

[Text version]
Cell line name LIM2537
Synonyms LIM 2537; LIM-2537
Accession CVCL_4441
Resource Identification Initiative To cite this cell line use: LIM2537 (RRID:CVCL_4441)
Comments From: Ludwig Institute for Cancer Research, Melbourne Branch; Melbourne; Australia.
Doubling time: 30 hours (CBA=CBA-0168).
Microsatellite instability: Instable (MSI) (PubMed=19378335; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colorectal adenocarcinoma (NCIt: C5105)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): CBA; PubMed=25926053

Markers:
AmelogeninX
CSF1PO9
D2S133823
D3S135815,16
D5S81810
D7S8208,11
D8S117912,13,14
D13S3178,13,14 (CBA)
8,14 (PubMed=25926053)
D16S53912
D18S5116,17,18,19
D19S43312,14
D21S1128,29,30
FGA23,24
TH016
TPOX8,9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=11606375
Philp A.J., Campbell I.G., Leet C., Vincan E., Rockman S.P., Whitehead R.H., Thomas R.J.S., Phillips W.A.
The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.
Cancer Res. 61:7426-7429(2001)

PubMed=19378335; DOI=10.1002/ijc.24289
Zhang H.-H., Walker F., Kiflemariam S., Whitehead R.H., Williams D., Phillips W.A., Mikeska T., Dobrovic A., Burgess A.W.
Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Int. J. Cancer 125:297-307(2009)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) CBA; CBA-0168
Cell line databases/resources cancercelllines; CVCL_4441
ColonAtlas; LIM2537
Biological sample resources BioSample; SAMN07624438
Encyclopedic resources Wikidata; Q54902538
Gene expression databases GEO; GSM1448135
Polymorphism and mutation databases Cosmic; 1238057
Cosmic; 1482514
Cosmic; 1486139
Cosmic; 1524338
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number25