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Cellosaurus IVG-BF/LXSN (CVCL_4417)

[Text version]
Cell line name IVG-BF/LXSN
Synonyms IVG-BF.LXSN
Accession CVCL_4417
Resource Identification Initiative To cite this cell line use: IVG-BF/LXSN (RRID:CVCL_4417)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Caution: Was briefly displayed in Cell Bank Australia under catalog number CBA-0058 but was never intended to be distributed.
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=22829774; DOI=10.1371/journal.pgen.1002772; PMCID=PMC3400581
Lovejoy C.A., Li W.-D., Reisenweber S., Thongthip S., Bruno J., de Lange T., De S., Petrini J.H.J., Sung P.A., Jasin M., Rosenbluh J., Zwang Y., Weir B.A., Hatton C., Ivanova E.V., MacConaill L.E., Hanna M., Hahn W.C., Lue N.F., Reddel R.R., Jiao Y.-C., Kinzler K.W., Vogelstein B., Papadopoulos N., Meeker A.K.
ALT Starr Cancer Consortium
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
PLoS Genet. 8:e1002772.1-e1002772.16(2012)

Cross-references
Encyclopedic resources Wikidata; Q54898382
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number13