Cellosaurus cell line IVG-BF/LXSN (CVCL

Cellosaurus IVG-BF/LXSN (CVCL_4417)

Cross-references
Cell line name	IVG-BF/LXSN
Synonyms	IVG-BF.LXSN
Accession	CVCL_4417
Resource Identification Initiative	To cite this cell line use: IVG-BF/LXSN (RRID:CVCL_4417)
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Caution: Was briefly displayed in Cell Bank Australia under catalog number CBA-0058 but was never intended to be distributed.
Disease	Li-Fraumeni syndrome (NCIt: C3476) Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=22829774; DOI=10.1371/journal.pgen.1002772; PMCID=PMC3400581 Courtney A. Lovejoy, Wen-Di Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H.J. Petrini, Patricia A. Sung, Maria Jasin, Joseph Rosenbluh ...Show all 25 authors... , Yaara Zwang, Barbara A. Weir, Charlie Hatton, Elena V. Ivanova, Laura Eleanor MacConaill, Megan Hanna, William Chun Hahn, Neal F. Lue, Roger Robert Reddel, Yu-Chen Jiao, Kenneth Wayne Kinzler, Bert Vogelstein, Nickolas Papadopoulos, Alan K. Meeker; Show fewer authors ALT Starr Cancer Consortium Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet. 8:e1002772.1-e1002772.16(2012)
Encyclopedic resources	Wikidata; Q54898382
Entry history
Entry creation	04-Apr-2012
Last entry update	14-Aug-2025
Version number	14