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Cellosaurus RWP-1 (CVCL_4373)

[Text version]
Cell line name RWP-1
Synonyms RWP 1; RWP1; Roger Williams Pancreatic-1
Accession CVCL_4373
Resource Identification Initiative To cite this cell line use: RWP-1 (RRID:CVCL_4373)
Comments Doubling time: 45 hours (PubMed=7083162; PubMed=8026879); 23.6 +- 0.54 hours (PubMed=27067801).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 57Y
Category Cancer cell line
Web pages Info; Pawefish; -; https://www.cellosaurus.org/pawefish/PancCellLineDescriptions/RWP-1.html
Publications

PubMed=7083162
Daniel L. Dexter, George M. Matook, Patricia A. Meitner, Hendrik A. Bogaars, Grant A. Jolly, Michael D. Turner, Paul Calabresi;
Establishment and characterization of two human pancreatic cancer cell lines tumorigenic in athymic mice.
Cancer Res. 42:2705-2714(1982)

PubMed=8026879; DOI=10.1002/ijc.2910580207
Georgina Berrozpe, James Schaeffer, Miguel Angel Peinado, Francisco X. Real, Manuel Perucho;
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.
Int. J. Cancer 58:185-191(1994)

PubMed=9665481; DOI=10.1016/S0002-9440(10)65561-7; PMCID=PMC1852940
Rosanna Paciucci, Maya R. Vila, Teresa Adell, Victor M. Diaz, Montserrat Tora, Toshikazu Nakamura, Francisco X. Real;
Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met.
Am. J. Pathol. 153:201-212(1998)

PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C
Vorapan Sirivatanauksorn, Yongyut Sirivatanauksorn, Patricia A. Gorman, Jeffrey M. Davidson, Denise Sheer, Patrick S. Moore, Aldo Scarpa, Paul A.W. Edwards, Nicholas Robert Lemoine;
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
Int. J. Cancer 91:350-358(2001)

PubMed=11787853; DOI=10.1007/s004280100474
Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12800145; DOI=10.1002/gcc.10218
Jose Adelaide, Huai-En Huang, Anne Murati, Amber E. Alsop, Beatrice Orsetti, Marie-Joelle Mozziconacci, Cornel Popovici, Christophe Ginestier, Anne Letessier, Celine Basset, Celine Courtay-Cahen ...Show all 16 authors... , Jocelyne Jacquemier, Charles Theillet, Daniel Birnbaum, Paul A.W. Edwards, Max Chaffanet; Show fewer authors
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Genes Chromosomes Cancer 37:333-345(2003)

PubMed=19077451; DOI=10.1159/000178871
Tomohiko Harada, Claude Chelala, Tatjana Crnogorac-Jurcevic, Nicholas Robert Lemoine;
Genome-wide analysis of pancreatic cancer using microarray-based techniques.
Pancreatology 9:13-24(2009)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
Richard Marcotte, Kevin R. Brown, Fernando Jose Suarez Saiz, Azin Sayad, Konstantina Karamboulas, Paul M. Krzyzanowski, Fabrice Sircoulomb, Mauricio Medrano, Yaroslav Fedyshyn, Judice Lie-Yong Koh, Dewald van Dyk ...Show all 28 authors... , Bohdana Fedyshyn, Marianna Luhova, Glauber C. Brito, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Alessandro Datti, Dahlia Kasimer, Alla Buzina, Patricia Mero, Christine Misquitta, Josee Normand, Maliha Haider, Troy Ketela, Jeffrey L. Wrana, Robert Rottapel, Benjamin G. Neel, Jason Moffat; Show fewer authors
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

PubMed=27067801; DOI=10.1186/s12885-016-2297-y; PMCID=PMC4828819
Kotaro Miura, Kenjiro Kimura, Ryosuke Amano, Sadaaki Yamazoe, Go Ohira, Akihiro Murata, Kohei Nishio, Tsuyoshi Hasegawa, Masakazu Yashiro, Bunzo Nakata, Masaichi Ohira, Kosei Hirakawa;
Establishment and characterization of new cell lines of anaplastic pancreatic cancer, which is a rare malignancy: OCUP-A1 and OCUP-A2.
BMC Cancer 16:268.1-268.13(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4373
Encyclopedic resources Wikidata; Q54951495
Experimental variables resources EFO; EFO_0022417
Gene expression databases GEO; GSM244429
Polymorphism and mutation databases Cosmic; 710870
Cosmic; 948739
Progenetix; CVCL_4373
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27