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Cellosaurus PDVC 57B (CVCL_4271)

[Text version]
Cell line name PDVC 57B
Synonyms PDVC57B; PDVC57b; PDVC57; PDV.C57; PDV C57
Accession CVCL_4271
Resource Identification Initiative To cite this cell line use: PDVC 57B (RRID:CVCL_4271)
Comments Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Disease Spindle-cell squamous cell carcinoma of the mouse skin (NCIt: C21810)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/10 LP.
Hierarchy Parent: CVCL_5858 (PDV)
Sex of cell Sex unspecified
Age at sampling <1D
Category Cancer cell line

Fusenig N.E., Dzarlieva-Petrusevska R.T., Breitkreutz D.
Phenotypic and cytogenetic characteristics of different stages during spontaneous transformation of mouse keratinocytes in vitro.
Carcinog. Compr. Surv. 9:293-326(1985)

PubMed=2185890; DOI=10.1016/0092-8674(90)90523-H
Bremner R., Balmain A.
Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.
Cell 61:407-417(1990)

Buchmann A., Ruggeri B., Klein-Szanto A.J.P., Balmain A.
Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7.
Cancer Res. 51:4097-4101(1991)

PubMed=1934268; DOI=10.1093/carcin/12.10.1875
Quintanilla M., Haddow S., Jonas D., Jaffe D., Bowden G.T., Balmain A.
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.
Carcinogenesis 12:1875-1881(1991)

PubMed=12807763; DOI=10.1093/carcin/bgg067
Zoumpourlis V., Solakidi S., Papathoma A., Papaevangeliou D.
Alterations in signal transduction pathways implicated in tumour progression during multistage mouse skin carcinogenesis.
Carcinogenesis 24:1159-1165(2003)

Cell line collections (Providers) CancerTools; 151630
ECACC; 01022129
Ximbio; 151630
Encyclopedic resources Wikidata; Q54946871
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13