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Cellosaurus Do-11-10 (CVCL_4163)

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Cell line name Do-11-10
Synonyms DO-11.10; DO 11.10; Do11.10; DO11.10
Accession CVCL_4163
Resource Identification Initiative To cite this cell line use: Do-11-10 (RRID:CVCL_4163)
Comments Characteristics: T-cell hybridoma originally elicited by vaccination of BALB/c mice (H-2d haplotype) with chicken ovalbumin. Popular model system to study CD4+ T cell responses.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3896 (BW5147)
Children:
CVCL_U810 (DMyc3-45)CVCL_U811 (DMyc9-36)CVCL_WK48 (Do-11-10 mutant 51)
Category Hybridoma
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/d/cell-lines-detail-77.html
Publications

PubMed=6185566; DOI=10.4049/jimmunol.130.3.1033
Janice White, Kathryn M. Haskins, Philippa Marrack, John Wayne Kappler;
Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies.
J. Immunol. 130:1033-1037(1983)

PubMed=10200546; DOI=10.1038/sj.cdd.4400447
Grant Morgan, Sallie Smith, John Pak, Ann Marshak-Rothstein, Rafael Fissore, Barbara Osborne;
Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway.
Cell Death Differ. 6:36-47(1999)

PubMed=10590261; DOI=10.1093/intimm/11.12.1957
Yoshihiro Takemoto, Masaaki Furuta, Mitsuru Sato, Masato Kubo, Yasuhiro Hashimoto;
Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3.
Int. Immunol. 11:1957-1964(1999)

PubMed=23110081; DOI=10.1371/journal.pone.0047585; PMCID=PMC3479146
Benjamin M. Roy, Dmitriy V. Zhukov, Jennifer A. Maynard;
Flanking residues are central to DO11.10 T cell hybridoma stimulation by ovalbumin 323-339.
PLoS ONE 7:e47585.1-e47585.11(2012)

Cross-references
Cell line collections (Providers) ECACC; 85082301
Cell line databases/resources Lonza; 881
TOKU-E; 4126
Anatomy/cell type resources BTO; BTO_0004333
Encyclopedic resources Wikidata; Q54831338
Experimental variables resources EFO; EFO_0022775
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number15