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Cellosaurus SK-PC-1 (CVCL_4054)

[Text version]
Cell line name SK-PC-1
Synonyms SK-PC1; PC1
Accession CVCL_4054
Resource Identification Initiative To cite this cell line use: SK-PC-1 (RRID:CVCL_4054)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Doubling time: 51.8 hours (PubMed=7723277).
Omics: Transcriptomics; Microarray.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8026879; DOI=10.1002/ijc.2910580207
Georgina Berrozpe, James Schaeffer, Miguel Angel Peinado, Francisco X. Real, Manuel Perucho;
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.
Int. J. Cancer 58:185-191(1994)

PubMed=7723277
Maya R. Vila, Josep Lloreta, Martina H. Schussler, Georgina Berrozpe, Sydney Welt, Francisco X. Real;
New pancreas cancers cell lines that represent distinct stages of ductal differentiation.
Lab. Invest. 72:395-404(1995)

PubMed=9665481; DOI=10.1016/S0002-9440(10)65561-7; PMCID=PMC1852940
Rosanna Paciucci, Maya R. Vila, Teresa Adell, Victor M. Diaz, Montserrat Tora, Toshikazu Nakamura, Francisco X. Real;
Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met.
Am. J. Pathol. 153:201-212(1998)

PubMed=11169957; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1014>3.0.CO;2-U
Christine Wallrapp, Susanne Hahnel, Wolfgang Boeck, Anja Soder, Antoaneta Mincheva, Peter Lichter, Gerhard Leder, Frank Gansauge, Claudio Sorio, Aldo Scarpa, Thomas M. Gress;
Loss of the Y chromosome is a frequent chromosomal imbalance in pancreatic cancer and allows differentiation to chronic pancreatitis.
Int. J. Cancer 91:340-344(2001)

PubMed=11787853; DOI=10.1007/s004280100474
Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
Richard Marcotte, Kevin R. Brown, Fernando Jose Suarez Saiz, Azin Sayad, Konstantina Karamboulas, Paul M. Krzyzanowski, Fabrice Sircoulomb, Mauricio Medrano, Yaroslav Fedyshyn, Judice Lie-Yong Koh, Dewald van Dyk ...Show all 28 authors... , Bohdana Fedyshyn, Marianna Luhova, Glauber C. Brito, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Alessandro Datti, Dahlia Kasimer, Alla Buzina, Patricia Mero, Christine Misquitta, Josee Normand, Maliha Haider, Troy Ketela, Jeffrey L. Wrana, Robert Rottapel, Benjamin G. Neel, Jason Moffat; Show fewer authors
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

DOI=10.4172/2324-9293.1000104
Markus Udo Wagenhauser, Felix Ruckert, Marco Niedergethmann, Robert Grutzmann, Hans-Detlev Saeger;
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4054
Anatomy/cell type resources BTO; BTO_0002823
Encyclopedic resources Wikidata; Q54954514
Polymorphism and mutation databases Cosmic; 710871
Cosmic; 948737
IARC_TP53; 3386
IARC_TP53; 16744
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number19