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Cellosaurus UACC-2087 (CVCL_4041)

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Cell line name UACC-2087
Synonyms UACC 2087; UACC2087; University of Arizona Cell Culture-2087
Accession CVCL_4041
Resource Identification Initiative To cite this cell line use: UACC-2087 (RRID:CVCL_4041)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val216Met (c.646G>A); ClinVar=VCV000182965; Zygosity=Unspecified (ATCC=CRL-3180).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3180

Markers:
AmelogeninX
CSF1PO11
D7S82010,12
D13S3178,10
D16S53911
TH019,9.3
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=7842014; DOI=10.1038/ng1094-155
Xin-Yuan Guan, Paul S. Meltzer, William S. Dalton, Jeffrey M. Trent;
Identification of cryptic sites of DNA sequence amplification in human breast cancer by chromosome microdissection.
Nat. Genet. 8:155-161(1994)

PubMed=9778046; DOI=10.1038/sj.onc.1202086
Judd Christopher Rice, Kathy S. Massey-Brown, Bernard W. Futscher;
Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells.
Oncogene 17:1807-1812(1998)

PubMed=15153330; DOI=10.1593/neo.3292; PMCID=PMC1502105
George S. Watts, Marc M. Oshiro, Damian J. Junk, Ryan J. Wozniak, Summer J. Watterson, Frederick E. Domann, Bernard W. Futscher;
The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
Neoplasia 6:187-194(2004)

Cross-references
Cell line collections (Providers) ATCC; CRL-3180
Encyclopedic resources Wikidata; Q54973820
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number14