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Cellosaurus OV-MZ-06 (CVCL_4005)

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Cell line name OV-MZ-06
Synonyms OV-MZ-6; OVMZ-6; OVarian-MainZ-06
Accession CVCL_4005
Resource Identification Initiative To cite this cell line use: OV-MZ-06 (RRID:CVCL_4005)
Comments Doubling time: 28 hours (PubMed=1500230).
Omics: Transcriptomics; Microarray.
Caution: Indicated as originating from a 70 year old patient in PubMed=1500230 and from a 59 year old patient in PubMed=11925137.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_X988 (OV-MZ-6#8)
Sex of cell Female
Age at sampling 70Y
Category Cancer cell line
Publications

PubMed=1500230; DOI=10.1002/ijc.2910520115
Volker Jochen Mobus, Claus-Dieter Gerharz, U. Press, Roland Moll, Timothy Beck, Walter Mellin, Kunhard Pollow, Paul-Georg Knapstein, Rolf Kreienberg;
Morphological, immunohistochemical and biochemical characterization of 6 newly established human ovarian carcinoma cell lines.
Int. J. Cancer 52:76-84(1992)

PubMed=21559638; DOI=10.3892/ijo.5.4.753
Christine Will, Olaf G. Wilhelm, Sandra Hohl, Volker Jochen Mobus, Ulrich H. Weidle, Rolf Kreienberg, Fritz Janicke, Manfred Schmitt, Henner Graeff;
Expression of urokinase-type plasminogen-activator (uPA) and its receptor (uPAR) in human ovarian-cancer cells and in-vitro invasion capacity.
Int. J. Oncol. 5:753-761(1994)

PubMed=11242531; DOI=10.1089/10430340150504019
Ansgar Bruning, Tanja Kohler, Sven Roy Quist, Shan Wang-Gohrke, Volker Jochen Mobus, Rolf Kreienberg, Ingo Bernard Runnebaum;
Adenoviral transduction efficiency of ovarian cancer cells can be limited by loss of integrin beta3 subunit expression and increased by reconstitution of integrin alphaVbeta3.
Hum. Gene Ther. 12:391-399(2001)

PubMed=11925137; DOI=10.1006/gyno.2002.6597
Matthias Oppitz, Volker Jochen Mobus, S. Brock, Ulrich Drews;
Muscarinic receptors in cell lines from ovarian carcinoma: negative correlation with survival of patients.
Gynecol. Oncol. 85:159-164(2002)

PubMed=15153938; DOI=10.1038/sj.cgt.7700727
Sven Roy Quist, Shan Wang-Gohrke, Tanja Kohler, Rolf Kreienberg, Ingo Bernard Runnebaum;
Cooperative effect of adenoviral p53 gene therapy and standard chemotherapy in ovarian cancer cells independent of the endogenous p53 status.
Cancer Gene Ther. 11:547-554(2004)

DOI=10.5282/edoc.3898
Nicole Isabel Euer;
Identification of target genes for the therapy and diagnosis of ovarian carcinoma.
Thesis PhD (2005); Ludwig Maximilians University of Munich; Munich; Germany

PubMed=15706405; DOI=10.3892/or.13.3.375
Nicole Isabel Euer, Sepp Kaul, Helmut Deissler, Volker Jochen Mobus, Robert Zeillinger, Ulrich H. Weidle;
Identification of L1CAM, Jagged2 and neuromedin U as ovarian cancer-associated antigens.
Oncol. Rep. 13:375-387(2005)

Cross-references
Anatomy/cell type resources BTO; BTO_0004487
Encyclopedic resources Wikidata; Q54936868
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number16