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Cellosaurus NCI-H1264 (CVCL_3970)

[Text version]
Cell line name NCI-H1264
Synonyms H1264; H-1264
Accession CVCL_3970
Resource Identification Initiative To cite this cell line use: NCI-H1264 (RRID:CVCL_3970)
Comments Problematic cell line: Contaminated. NCI-H157 and NCI-H1264 have been shown to be identical.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00410.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (from autologous cell line NCI-H157).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Unspecified (PubMed=1311061; PubMed=12068308).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu298Ter (c.892G>T); ClinVar=VCV000093323; Zygosity=Unspecified (PubMed=1311061).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0463 ! NCI-H157
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-5860

Markers:
AmelogeninX
CSF1PO12
D5S81810,13
D7S82011,12
D13S31712
D16S53912,13
TH017,9
TPOX6,12
vWA15

Run an STR similarity search on this cell line
Web pages Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/cross-contamination-of-atcc-crl-5802-and-atcc-crl-5860
Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/misidentified-cell-lines-atcc-crl-5802-and-atcc-crl-5860
Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/nci-h1264-atcc-crl-5860
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=1311061
Tetsuya Mitsudomi, Seth M. Steinberg, Marion M. Nau, David P. Carbone, Domenico D'Amico, Sara M. Bodner, Herbert Kazuto Oie, Ritva Ilona Linnoila, James L. Mulshine, John D. Minna, Adi F. Gazdar;
p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.
Oncogene 7:171-180(1992)

PubMed=1563005
Giuseppe Giaccone, James Battey, Adi F. Gazdar, Herbert Kazuto Oie, Muriel Draoui, Terry W. Moody;
Neuromedin B is present in lung cancer cell lines.
Cancer Res. 52:2732s-2736s(1992)

PubMed=8806092; DOI=10.1002/jcb.240630505
Ruby M. Phelps, Bruce E. Johnson, Daniel C. Ihde, Adi F. Gazdar, David P. Carbone, Patrick R. McClintock, Ritva Ilona Linnoila, Mary J. Matthews, Paul A. Bunn Jr., Desmond Niall Carney, John D. Minna, James L. Mulshine;
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. Suppl. 24:32-91(1996)

PubMed=9649128; DOI=10.1038/bjc.1998.361; PMCID=PMC2150402
Seung Yi, Jing-Ru Chen, Jean Viallet, Ralph H. Schwall, T. Nakamura, Ming-Sound Tsao;
Paracrine effects of hepatocyte growth factor/scatter factor on non-small-cell lung carcinoma cell lines.
Br. J. Cancer 77:2162-2170(1998)

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Sanjay Modi, Akihito Kubo, Herbert Kazuto Oie, Amy B. Coxon, Ahad Rehmatulla, Frederic J. Kaye;
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=11369051; DOI=10.1016/S0165-4608(00)00363-0
Catherine Luk, Ming-Sound Tsao, Jane Bayani, Frances Alice Shepherd, Jeremy Andrew Squire;
Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization.
Cancer Genet. Cytogenet. 125:87-99(2001)

PubMed=12068308; DOI=10.1038/nature00766
Helen R. Davies, Graham Robert Bignell, Charles Cox, Philip J. Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil Davis ...Show all 52 authors... , Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry Austin Gusterson, Colin S. Cooper, Janet M. Shipley, Darren Hargrave, Kathy Pritchard-Jones, Norman J. Maitland, Georgia Chenevix-Trench, Gregory J. Riggins, Darell Doty Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew Nicholson, Judy W.C. Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard Foster Seigler, Timothy L. Darrow, Hugh F. Paterson, Richard Marais, Christopher John Marshall, Richard Wooster, Michael Rudolf Stratton, P. Andrew Futreal; Show fewer authors
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084
James L. Mulshine, Peter Ujhazy, Melissa Antman, Christine M. Burgess, Igor A. Kuzmin, Paul A. Bunn Jr., Bruce E. Johnson, Jack Alan Roth, Harvey I. Pass, Sheila M. Ross, Carolyn R. Aldige ...Show all 13 authors... , Ignacio Ivan Wistuba, John D. Minna; Show fewer authors
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-5860 - Discontinued
KCLB; 91264 - Discontinued
Cell line databases/resources cancercelllines; CVCL_3970
Anatomy/cell type resources BTO; BTO_0003012
Biological sample resources BioSample; SAMN03151857
BioSample; SAMN03472576
Encyclopedic resources Wikidata; Q54907785
Polymorphism and mutation databases Cosmic; 724865
Cosmic; 844600
Cosmic; 877262
Cosmic; 877416
Cosmic; 903584
Cosmic; 930490
Cosmic; 1152508
Cosmic; 2560226
IARC_TP53; 487
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number31