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Cellosaurus NCI-H460M (CVCL_3969)

[Text version]
Cell line name NCI-H460M
Synonyms H460M; H-460M; H460-M
Accession CVCL_3969
Resource Identification Initiative To cite this cell line use: NCI-H460M (RRID:CVCL_3969)
Comments Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0459 (NCI-H460)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Cell line databases/resources cancercelllines; CVCL_3969
Anatomy/cell type resources BTO; BTO:0002836
Encyclopedic resources Wikidata; Q54908064
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17