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Cellosaurus A818-4 (CVCL_3892)

[Text version]
Cell line name A818-4
Synonyms A-818-4; A 818-4; A818.4; A818 4; A8184; 818-4; 818_4; 818.4; 8184
Accession CVCL_3892
Secondary accession CVCL_0128
Resource Identification Initiative To cite this cell line use: A818-4 (RRID:CVCL_3892)
Comments Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3890 (A818)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=1764370; DOI=10.1038/bjc.1991.467; PMCID=PMC1977874
Claire M. Barton, Susan Louise Staddon, Christine M. Hughes, Peter A. Hall, Catriona O'Sullivan, Gunter Kloppel, Belinda Theis, Ronald Christopher Gordon Russell, John Neoptolemos, Robin Charles Noel Williamson, David Philip Lane, Nicholas Robert Lemoine;
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.
Br. J. Cancer 64:1076-1082(1991)

PubMed=1906154
Holger Kalthoff, Christian Roeder, Inge Humburg, Heinz-Gunter Thiele, Heiner Greten, Wolff Helmut Schmiegel;
Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells.
Oncogene 6:1015-1021(1991)

PubMed=8426738
Holger Kalthoff, Wolff Helmut Schmiegel, Christian Roeder, Daniela Kasche, Andreas Schmidt, Georg Lauer, Heinz-Gunter Thiele, Georg Honold, Klaus Pantel, Gert Riethmuller, Ewalt Scherer ...Show all 14 authors... , Julian Maurer, Heiko Maacke, Wolfgang Deppert; Show fewer authors
p53 and K-RAS alterations in pancreatic epithelial cell lesions.
Oncogene 8:289-298(1993)

PubMed=8430098; DOI=10.1073/pnas.90.3.863; PMCID=PMC45770
Wolff Helmut Schmiegel, Christian Roeder, Jan Schmielau, Ulrich Rodeck, Holger Kalthoff;
Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 90:863-867(1993)

PubMed=9472115; DOI=10.3892/ijo.12.3.717
Carsten Muller, Andreas Clemens Grosse Bockhorn, Simone Klusmeier, Michael Kiehl, Christian Roeder, Holger Kalthoff, Olaf M. Koch;
Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis.
Int. J. Oncol. 12:717-723(1998)

PubMed=10415853; DOI=10.1111/j.1749-6632.1999.tb09512.x
Lasse Lehnert, Hartwig Trost, Wolff Helmut Schmiegel, Christian Roeder, Holger Kalthoff;
Hollow-spheres: a new model for analyses of differentiation of pancreatic duct epithelial cells.
Ann. N. Y. Acad. Sci. 880:83-93(1999)

PubMed=11787853; DOI=10.1007/s004280100474
Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12692724; DOI=10.1007/s00428-003-0784-4
Bence Sipos, Simone Moser, Holger Kalthoff, Virag Torok, Johannes-Matthias Lohr, Gunter Kloppel;
A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform.
Virchows Arch. 442:444-452(2003)

Cross-references
Cell line databases/resources MCCL; MCC:0000020
cancercelllines; CVCL_3892
Encyclopedic resources Wikidata; Q54607225
Polymorphism and mutation databases Cosmic; 710850
Cosmic; 736267
Cosmic; 808168
Cosmic; 933525
Cosmic; 1108342
Cosmic; 1320466
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20