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Cellosaurus HOUA-I (CVCL_3867)

[Text version]

Cell line name HOUA-I
Synonyms HOUA-1; HOUAI; HOUA
Accession CVCL_3867
Resource Identification Initiative To cite this cell line use: HOUA-I (RRID:CVCL_3867)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: ~50 hours (CelloPub=CLPUB00051); 56 hours (PubMed=10457904).
Misspelling: HOOUA; In Cosmic 1241348.
Derived from sampling site: Endometrium.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=8105795).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=8105795).
Disease Endometrial carcinoma (NCIt: C7558)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A778 ! HOUA-II
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): DepMap; RCB

Markers:
AmelogeninX
CSF1PO13,14,15 (DepMap)
14,15 (RCB)
D3S135816,17
D5S81812,13,14,15 (DepMap)
12,14,15 (RCB)
D7S82010,11,12
D8S117912,13,15
D13S31713,14,15
D16S5399,13,14 (RCB)
9,13,14,15 (DepMap)
D18S5117,18,19,23,24,25
D21S1131,32
FGA17,21
Penta D11
Penta E13,15,16
TH016,9
TPOX8,9
vWA18,19,20

Run an STR similarity search on this cell line
Publications

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Ishiwata I., Ishiwata C., Nozawa S., Ishikawa H.
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Ishiwata I., Ishiwata C., Soma M., Ono I., Nakaguchi T., Ishikawa H.
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

CLPUB00051
Ishikawa I., Soma M., Ono I., Nakaguchi T., Ishawata C.
Biological characteristics of adenocarcinoma cell line (HOUA-I) and B-lymphoblastoid cell line (HOUA-II) established from the same tissue of endometrial adenocarcinoma.
Jikeikai Med. J. 36:303-315(1989)

PubMed=8105795; DOI=10.1002/mc.2940080303
Enomoto T., Fujita M., Inoue M., Nakazawa-Miyamoto A., Tanizawa O., Nomura T.
Alterations of the Rb gene and its association with Ki-ras activation and p53 inactivation in endometrial adenocarcinoma.
Mol. Carcinog. 8:132-137(1993)

PubMed=9436037
Soma M., Ishiwata I., Ishiwata C., Nakaguchi T., Ono I., Kiguchi K., Hashimoto H., Tachibana T., Ishikawa H., Nozawa S.
Tissue reconstruction of gynecologic tumor cells in the rotation culture system.
Hum. Cell 10:175-181(1997)

PubMed=10457904
Ishiwata I., Sudo T., Kiguchi K., Ishikawa H.
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=15901131; DOI=10.1016/j.prp.2005.01.002
Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y.
Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines.
Pathol. Res. Pract. 201:109-115(2005)

Cross-references
Cell line collections RCB; RCB0659
Cell line databases/resources CLO; CLO_0050886
DepMap; ACH-002027
Biological sample resources BioSample; SAMN03472265
Encyclopedic resources Wikidata; Q54890187
Polymorphism and mutation databases Cosmic; 713498
Cosmic; 1241348
Cosmic; 1622897
IARC_TP53; 2378
Entry history
Entry creation04-Apr-2012
Last entry update16-Dec-2021
Version number21