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Cellosaurus (CVCL_3842)

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Comments Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9518.
Biotechnology: Used for mutation assays to predict the carcinogenic potential of chemicals. Allows the quantitation of forward mutations at the thymidine kinase (TK) locus. These TK heterozygous cells are treated with a range of doses of the test substance. The cells are incubated, washed free of tests substance and allowed time for the phenotypic expression of newly induced mutations (PubMed=1093012; PubMed=3416837; PubMed=4360720; PubMed=7329431).
Doubling time: ~10 hours (Note=Lot 02052008) (JCRB=JCRB0709.1).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse thymic lymphoma (NCIt: C134997)
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_4235 (L-5178-Y-S)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications


Wilma Keijzer, Dirk Bootsma;
A third complementation group in xeroderma pigmentosum.
Mutat. Res. 22:87-91(1974)



lymphoblastoid cell lines.
Mutat. Res. 107:387-396(1983)



mutants isolated from a continuous rat-liver epithelial cell line.
Mutat. Res. 107:433-445(1983)



chromatid aberrations in X-irradiated human lymphocytes.
Mutagenesis 7:285-290(1992)



patients and healthy volunteers.
Mutat. Res. 588:1-6(2005)




Endocrinology 152:4138-4147(2011)

Cross-references
Cell line collections (Providers) ATCC; CRL-9518
BCRC; 60112
BCRJ; 0140
Hysigen; TCM-C740
JCRB; FDSC0053 - Discontinued
JCRB; JCRB0709.1
Cell line databases/resources CLO; CLO_0007196
CCRID; 1101MOU-PUMC000816
CCRID; 3101MOUTCM33
Encyclopedic resources Wikidata; Q54901039
Entry history
Entry creation04-Apr-2012
Last entry update25-Jun-2026
Version number20