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Cellosaurus SV-HUC-1 (CVCL_3798)

[Text version]
Cell line name SV-HUC-1
Synonyms HUC-1; SV-HUC; SVHUC
Accession CVCL_3798
Resource Identification Initiative To cite this cell line use: SV-HUC-1 (RRID:CVCL_3798)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9520.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Deep exome analysis.
Derived from site: In situ; Ureter; UBERON=UBERON_0000056.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IP86 (MC-SV-HUC T-1)CVCL_IP89 (MC-SV-HUC T-10)CVCL_IP90 (MC-SV-HUC T-11)
CVCL_IP91 (MC-SV-HUC T-16)CVCL_6418 (MC-SV-HUC T-2)CVCL_IP87 (MC-SV-HUC T-7)
CVCL_IP88 (MC-SV-HUC T-9)CVCL_A0BS (SV-HUC-MAr)CVCL_A0BZ (SV-HUC-TGr/Gr)
CVCL_IP92 (SV-HUC/ras-A)CVCL_IP93 (SV-HUC/ras-B)CVCL_IP94 (SV-HUC/ras-C)
CVCL_IP95 (SV-HUC/ras-D)CVCL_IP96 (SV-HUC/ras-E)CVCL_IP97 (SV-HUC/ras-F)
CVCL_IP98 (SV-HUC/ras-G)
Sex of cell Male
Age at sampling 11Y
Category Transformed cell line
STR profile Source(s): ATCC; PubMed=27270441

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81812,14
D7S82010,11
D13S31712,13
D16S53911
TH019,9.3
TPOX8,10
vWA14

Run an STR similarity search on this cell line
Web pages https://www.synapse.org/UC25
Publications

PubMed=2822239
Christian B.J., Loretz L.J., Oberley T.D., Reznikoff C.A.
Characterization of human uroepithelial cells immortalized in vitro by simian virus 40.
Cancer Res. 47:6066-6073(1987)

PubMed=2835156
Meisner L.F., Wu S.-Q., Christian B.J., Reznikoff C.A.
Cytogenetic instability with balanced chromosome changes in an SV40 transformed human uroepithelial cell line.
Cancer Res. 48:3215-3220(1988)

PubMed=2841047; DOI=10.1093/carcin/9.8.1427
Reznikoff C.A., Loretz L.J., Christian B.J., Wu S.-Q., Meisner L.F.
Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene.
Carcinogenesis 9:1427-1436(1988)

Patent=US4980290
Reznikoff C.A., Christian B.J.
Human uroepithelial cell.
Patent number US4980290, 25-Dec-1990

PubMed=1767334; DOI=10.1007/BF01233620
Klingelhutz A.J., Wu S.-Q., Reznikoff C.A.
Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells.
Somat. Cell Mol. Genet. 17:551-565(1991)

PubMed=1311637
Klingelhutz A.J., Wu S.-Q., Huang J., Reznikoff C.A.
Loss of 3p13->p21.2 in tumorigenic reversion of a hybrid between isogeneic nontumorigenic and tumorigenic human uroepithelial cells.
Cancer Res. 52:1631-1634(1992)

PubMed=15846775; DOI=10.1002/gcc.20166
Williams S.V., Adams J., Coulter J., Summersgill B.M., Shipley J.M., Knowles M.A.
Assessment by M-FISH of karyotypic complexity and cytogenetic evolution in bladder cancer in vitro.
Genes Chromosomes Cancer 43:315-328(2005)

PubMed=27270441; DOI=10.1038/onc.2016.172
Nickerson M.L., Witte N., Im K.M., Turan S., Owens C., Misner K., Tsang S.X., Cai Z., Wu S., Dean M., Costello J.C., Theodorescu D.
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.
Oncogene 36:35-46(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-9520
BCRC; 60358
CLS; 305075
KCB; KCB 2012112YJ
Cell line databases/resources CLO; CLO_0009177
CCRID; 3101HUMTCHu169
Anatomy/cell type resources BTO; BTO:0003908
Biological sample resources BioSample; SAMN03471218
Encyclopedic resources Wikidata; Q54970934
Polymorphism and mutation databases Cosmic; 687554
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23