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Cellosaurus SV-HUC-1 (CVCL_3798)

[Text version]
Cell line name SV-HUC-1
Synonyms HUC-1; SV-HUC; SVHUC
Accession CVCL_3798
Resource Identification Initiative To cite this cell line use: SV-HUC-1 (RRID:CVCL_3798)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9520.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Ureter; UBERON=UBERON_0000056.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IP86 (MC-SV-HUC T-1)CVCL_IP89 (MC-SV-HUC T-10)CVCL_IP90 (MC-SV-HUC T-11)
CVCL_IP91 (MC-SV-HUC T-16)CVCL_6418 (MC-SV-HUC T-2)CVCL_IP87 (MC-SV-HUC T-7)
CVCL_IP88 (MC-SV-HUC T-9)CVCL_A0BS (SV-HUC-MAr)CVCL_A0BZ (SV-HUC-TGr/Gr)
CVCL_IP92 (SV-HUC/ras-A)CVCL_IP93 (SV-HUC/ras-B)CVCL_IP94 (SV-HUC/ras-C)
CVCL_IP95 (SV-HUC/ras-D)CVCL_IP96 (SV-HUC/ras-E)CVCL_IP97 (SV-HUC/ras-F)
CVCL_IP98 (SV-HUC/ras-G)
Sex of cell Male
Age at sampling 11Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-9520; PubMed=27270441

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133817
D3S135814,17
D5S81812,14
D7S82010,11
D8S117914,16
D13S31712,13
D16S53911
D18S5115,16
D19S43314
D21S1129,30
FGA21,22
Penta D13
Penta E10,20
TH019,9.3
TPOX8,10
vWA14

Run an STR similarity search on this cell line
Web pages Info; Synapse; Bladder Cancer exome; https://www.synapse.org/Synapse:syn4970200
Publications

PubMed=2822239
Brian J. Christian, Linda J. Loretz, Terry DeWayne Oberley, Catherine Armstrong Reznikoff;
Characterization of human uroepithelial cells immortalized in vitro by simian virus 40.
Cancer Res. 47:6066-6073(1987)

PubMed=2835156
Lorraine Faxon Meisner, Shi-Qi Wu, Brian J. Christian, Catherine Armstrong Reznikoff;
Cytogenetic instability with balanced chromosome changes in an SV40 transformed human uroepithelial cell line.
Cancer Res. 48:3215-3220(1988)

PubMed=2841047; DOI=10.1093/carcin/9.8.1427
Catherine Armstrong Reznikoff, Linda J. Loretz, Brian J. Christian, Shi-Qi Wu, Lorraine Faxon Meisner;
Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene.
Carcinogenesis 9:1427-1436(1988)

Patent=US4980290
Catherine Armstrong Reznikoff, Brian J. Christian;
Human uroepithelial cell.
Patent number US4980290, 25-Dec-1990

PubMed=1767334; DOI=10.1007/BF01233620
Aloysius J. Klingelhutz, Shi-Qi Wu, Catherine Armstrong Reznikoff;
Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells.
Somat. Cell Mol. Genet. 17:551-565(1991)

PubMed=1311637
Aloysius J. Klingelhutz, Shi-Qi Wu, Jin-Wen Huang, Catherine Armstrong Reznikoff;
Loss of 3p13->p21.2 in tumorigenic reversion of a hybrid between isogeneic nontumorigenic and tumorigenic human uroepithelial cells.
Cancer Res. 52:1631-1634(1992)

PubMed=15846775; DOI=10.1002/gcc.20166
Sarah V. Williams, Jacqui Adams, Jane Coulter, Brenda M. Summersgill, Janet M. Shipley, Margaret A. Knowles;
Assessment by M-FISH of karyotypic complexity and cytogenetic evolution in bladder cancer in vitro.
Genes Chromosomes Cancer 43:315-328(2005)

PubMed=27270441; DOI=10.1038/onc.2016.172; PMCID=PMC5140783
Michael L. Nickerson, Nicolle Witte, Kate McGee Im, Sevilay Turan, Charles R. Owens, Kevin Misner, Shirley X. Tsang, Zhi-Ming Cai, Sen Wu, Michael Dean, James C. Costello, Dan Theodorescu;
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.
Oncogene 36:35-46(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-9520
BCRC; 60358
CLS; 305075
KCB; KCB 2012112YJ
Cell line databases/resources CLO; CLO_0009177
CCRID; 3101HUMTCHu169
Anatomy/cell type resources BTO; BTO_0003908
Biological sample resources BioSample; SAMN03471218
Encyclopedic resources Wikidata; Q54970934
Polymorphism and mutation databases Cosmic; 687554
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26