Cellosaurus logo
expasy logo

Cellosaurus NL20T-A (CVCL_3757)

[Text version]
Cell line name NL20T-A
Synonyms NL20-TA; NL20TA
Accession CVCL_3757
Resource Identification Initiative To cite this cell line use: NL20T-A (RRID:CVCL_3757)
Comments Population: Caucasian.
Characteristics: Tumorigenic. Established from a subcutaneous tumor in an athymic nude mouse inoculated with the parent cell line (PubMed=8521416).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C5B5 (NL20T)
Sex of cell Female
Age at sampling 20Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2504

Markers:
AmelogeninX
CSF1PO11
D2S133821,24
D3S135814,17
D5S81812
D7S82012
D8S117912,13
D13S31711,12
D16S53912
D18S5114
D19S43313,15.2
D21S1129,31.2
FGA22,23
Penta D9,11
Penta E6,15,16
TH016,7
TPOX9,11
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=8521416
Joan H. Schiller, Gerard N. Bittner;
Loss of the tumorigenic phenotype with in vitro, but not in vivo, passaging of a novel series of human bronchial epithelial cell lines: possible role of an alpha5/beta1-integrin-fibronectin interaction.
Cancer Res. 55:6215-6221(1995)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-2504
Cell line databases/resources CLO; CLO_0008180
cancercelllines; CVCL_3757
Encyclopedic resources Wikidata; Q54930687
Gene expression databases GEO; GSM827477
Polymorphism and mutation databases Progenetix; CVCL_3757
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17