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Cellosaurus NL20T-A (CVCL_3757)

[Text version]
Cell line name NL20T-A
Synonyms NL20-TA; NL20TA
Accession CVCL_3757
Resource Identification Initiative To cite this cell line use: NL20T-A (RRID:CVCL_3757)
Comments Population: Caucasian.
Characteristics: Tumorigenic. Established from a subcutaneous tumor in an athymic nude mouse inoculated with the parent cell line (PubMed=8521416).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C5B5 (NL20T)
Sex of cell Female
Age at sampling 20Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2504

Markers:
AmelogeninX
CSF1PO11
D2S133821,24
D3S135814,17
D5S81812
D7S82012
D8S117912,13
D13S31711,12
D16S53912
D18S5114
D19S43313,15.2
D21S1129,31.2
FGA22,23
Penta D9,11
Penta E6,15,16
TH016,7
TPOX9,11
vWA14,17

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Publications

PubMed=8521416
Schiller J.H., Bittner G.N.
Loss of the tumorigenic phenotype with in vitro, but not in vivo, passaging of a novel series of human bronchial epithelial cell lines: possible role of an alpha5/beta1-integrin-fibronectin interaction.
Cancer Res. 55:6215-6221(1995)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-2504
Cell line databases/resources CLO; CLO_0008180
cancercelllines; CVCL_3757
Encyclopedic resources Wikidata; Q54930687
Gene expression databases GEO; GSM827477
Polymorphism and mutation databases Progenetix; CVCL_3757
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17