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Cellosaurus FHC (CVCL_3688)

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Cell line name FHC
Synonyms Fetal Human Colon
Accession CVCL_3688
Resource Identification Initiative To cite this cell line use: FHC (RRID:CVCL_3688)
Comments Characteristics: Forms solid tumors after transplantation into SCID mice.
Doubling time: ~62 hours (PubMed=6519668).
Karyotypic information: Is hypotriploid, has >20 copies of the 8q23~8q24.3 region containing MYC (PubMed=20193843).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Fetal colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 13FW
Category Spontaneously immortalized cell line
STR profile Source(s): AddexBio=P0009022/4980; ATCC=CRL-1831

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,20
D3S135816,18
D5S81812,13
D7S8208,12
D8S117914,17
D13S31712,13
D16S5399,11
D18S5115,17
D19S43313,14.2
D21S1128,29
FGA21,24.3
Penta D9,13
Penta E7,14
TH016,9.3
TPOX8,11
vWA16

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Publications

PubMed=6519668; DOI=10.1007/BF02619632
Khwaja Mohammad Siddiqui, Dharam P. Chopra;
Primary and long term epithelial cell cultures from human fetal normal colonic mucosa.
In Vitro 20:859-868(1984)

PubMed=20193843; DOI=10.1016/j.cancergencyto.2009.11.009
Karel Soucek, Pavla Gajduskova, Marie Brazdova, Martina Hyzd'alova, Lenka Koci, David Vydra, Radek Trojanec, Zuzana Pernicova, Lenka Lentvorska, Marian Hajduch, Jirina Hofmanova, Alois Kozubik;
Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation.
Cancer Genet. Cytogenet. 197:107-116(2010)

Cross-references
Cell line collections (Providers) AddexBio; P0009022/4980
ATCC; CRL-1831
KCB; KCB 2017068YJ
KCB; KCB 2018026YJ
Cell line databases/resources CLO; CLO_0003236
CCRID; 5301HUM-KCB18026YJ
Anatomy/cell type resources BTO; BTO_0003808
Biological sample resources BioSample; SAMN03471253
Chemistry resources ChEMBL-Cells; CHEMBL3308603
ChEMBL-Targets; CHEMBL614654
PubChem_Cell_line; CVCL_3688
Encyclopedic resources Wikidata; Q54834869
Gene expression databases GEO; GSM1448155
Polymorphism and mutation databases IARC_TP53; 28522
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23