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Cellosaurus WEHI-3 (CVCL_3622)

[Text version]
Cell line name WEHI-3
Synonyms Wehi-3; WEHI 3; WEHI3
Accession CVCL_3622
Resource Identification Initiative To cite this cell line use: WEHI-3 (RRID:CVCL_3622)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Doubling time: 18 hours (Note=In 2% FCS) (PubMed=3005406).
Transformant: DrugBank; DB11057; Mineral oil.
Omics: SNP array analysis.
Misspelling: WEIHI3; Note=Occasionally.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Children:
CVCL_0J48 (HUCL-1)CVCL_2239 (WEHI-3B)
Sex of cell Male
Age at sampling 6M
Category Cancer cell line
STR profile Source(s): PubMed=31220119

Mouse STR 1-115,16,18
Mouse STR 1-217
Mouse STR 2-116
Mouse STR 3-214,15
Mouse STR 4-221.3
Mouse STR 5-514
Mouse STR 6-418,19,20,21
Mouse STR 6-712,13,14
Mouse STR 7-125.2,26.2,27.2
Mouse STR 8-113,14
Mouse STR 11-218,19
Mouse STR 12-116,17
Mouse STR 13-115.2,16.2
Mouse STR 15-322.3,23.3,25.5
Mouse STR 17-216
Mouse STR 18-318
Mouse STR 19-212,13
Mouse STR X-126,27

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20201109215324/www.infarktforschung.de/macrophages_cell_lines.html

PubMed=5259325; DOI=10.1093/jnci/43.4.963
Warner N.L., Moore M.A.S., Metcalf D.
A transplantable myelomonocytic leukemia in BALB-c mice: cytology, karyotype, and muramidase content.
J. Natl. Cancer Inst. 43:963-982(1969)

PubMed=4543620; DOI=10.3181/00379727-144-37688
Rollinghoff M., Warner N.L.
Specificity of in vivo tumor rejection assessed by mixing immune spleen cells with target and unrelated tumor cells.
Proc. Soc. Exp. Biol. Med. 144:813-818(1973)

PubMed=6170720; DOI=10.1084/jem.154.5.1419
McKean D.J., Infante A.J., Nilson A., Kimoto M., Fathman C.G., Walker E., Warner N.L.
Major histocompatibility complex-restricted antigen presentation to antigen-reactive T cells by B lymphocyte tumor cells.
J. Exp. Med. 154:1419-1431(1981)

de Weger R.A., van Loveren H., van Basten C.D.H., Oskam R., van der Zeijst B.A.M., Den Otter W.
Functional activities of the NCTC 1469 macrophage-like cell line: comparison of the NCTC 1469 cell line with various other macrophage-like cell lines.
J. Reticuloendothel. Soc. 33:55-66(1983)

PubMed=3005406; DOI=10.4049/jimmunol.136.6.2181
Morel P.A., Manolagas S.C., Provvedini D.M., Wegmann D.R., Chiller J.M.
Interferon-gamma-induced IA expression in WEHI-3 cells is enhanced by the presence of 1,25-dihydroxyvitamin D3.
J. Immunol. 136:2181-2186(1986)

PubMed=3792703; DOI=10.1111/j.1432-0436.1986.tb00568.x
Leenen P.J.M., Jansen A.M.A.C., van Ewijk W.
Murine macrophage cell lines can be ordered in a linear differentiation sequence.
Differentiation 32:157-164(1986)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cell line collections (Providers) ATCC; TIB-68
BCRC; 60176
CLS; 400381
KCB; KCB 2012094YJ
RCB; RCB0035
Cell line databases/resources CLO; CLO_0009579
CLO; CLO_0051420
CLDB; cl4691
CCRID; 1101MOU-PUMC000029
Anatomy/cell type resources BTO; BTO:0000295
Biological sample resources BioSample; SAMN11397664
Encyclopedic resources Wikidata; Q54993760
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number25