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Cellosaurus NIT-2 (CVCL_3562)

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Cell line name NIT-2
Accession CVCL_3562
Resource Identification Initiative To cite this cell line use: NIT-2 (RRID:CVCL_3562)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BLKS/J-Cpefat/1 x NOD/Lt-Tg(RIPTag)1Lt.
Sex of cell Male
Age at sampling 10W
Category Transformed cell line
Publications

PubMed=9348219; DOI=10.1210/endo.138.11.5506
Oleg Varlamov, Lloyd D. Fricker, Hisasi Furukawa, Donald Frederick Steiner, Stephen H. Langley, Edward H. Leiter;
Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing.
Endocrinology 138:4883-4892(1997)

Cross-references
Cell line collections (Providers) ATCC; CRL-2364
Cell line databases/resources CLO; CLO_0008176
Encyclopedic resources Wikidata; Q54930634
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14