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Cellosaurus H9/HTLV-IIIB (CVCL_3514)

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Cell line name H9/HTLV-IIIB
Synonyms H9/HTLV-IIIB NIH 1983
Accession CVCL_3514
Resource Identification Initiative To cite this cell line use: H9/HTLV-IIIB (RRID:CVCL_3514)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8543.
Population: Caucasian.
Virology: In vitro infected by HIV-1.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene deletion; HGNC; HGNC:7208; MPDZ; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1240 (H9)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-8543

Markers:
AmelogeninX,Y
CSF1PO11
D2S133820,25
D3S135815,16
D5S81811
D7S8208,11
D8S117912,14
D13S3178,12
D16S53911,12
D18S5118
D19S43314
D21S1130
FGA21,25
Penta D9
Penta E13,15
TH018,9
TPOX8,9
vWA14,15

Run an STR similarity search on this cell line
Publications

Patent=US4520113
Robert Charles Gallo, Mikulas Popovic, Mangalasseril G. Sarngadharan;
Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions.
Patent number US4520113, 28-May-1985

PubMed=2567177; DOI=10.1089/aid.1989.5.253
Dean L. Mann, Stephen James O'Brien, Dennis A. Gilbert, Yvonne A. Reid, Mikulas Popovic, Elizabeth Lee Read-Connole, Robert Charles Gallo, Adi F. Gazdar;
Origin of the HIV-susceptible human CD4+ cell line H9.
AIDS Res. Hum. Retroviruses 5:253-255(1989)

Cross-references
Cell line collections (Providers) ATCC; CRL-8543
BEI_Resources; ARP-400
Cell line databases/resources CLO; CLO_0003613
cancercelllines; CVCL_3514
Encyclopedic resources Wikidata; Q54872246
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number25