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Cellosaurus 1A2 (CVCL_3480)

[Text version]
Cell line name 1A2
Accession CVCL_3480
Resource Identification Initiative To cite this cell line use: 1A2 (RRID:CVCL_3480)
Comments Group: Patented cell line.
Problematic cell line: Misclassified. Parent cell line (GM01500) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8119.
Population: Caucasian.
Characteristics: Secretes IgG2 kappa.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D870 (GM01500)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): ATCC=CRL-8119

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81810,12
D7S82010
D13S31712
D16S53911
TH019,9.3
TPOX8
vWA16,19

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Publications

Patent=US4834975
Anthony W. Siadak, Mark E. Lostrom;
Human monoclonal antibodies to serotypic lipopolysaccharide determinants on Gram-negative bacteria and their production.
Patent number US4834975, 30-May-1989

Patent=US5662905
Anthony W. Siadak, Mae Joanne Rosok;
Monoclonal antibody compositions cross-reactive and cross-protective against P. aeruginosa serotypes.
Patent number US5662905, 02-Sep-1997

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-8119 - Discontinued
ECACC; 93031502 - Discontinued
Cell line databases/resources CLO; CLO_0001146
IGRhCellID; 1A2
Biological sample resources BioSample; SAMN03471192
Encyclopedic resources Wikidata; Q54582644
Experimental variables resources EFO; EFO_0002094
Gene expression databases ArrayExpress; E-MTAB-38
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number28