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Cellosaurus HCC2688 (CVCL_3376)

[Text version]
Cell line name HCC2688
Synonyms Hamon Cancer Center 2688
Accession CVCL_3376
Resource Identification Initiative To cite this cell line use: HCC2688 (RRID:CVCL_3376)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*01:01,01:01
HLA-BB*08:01,08:01
HLA-CC*07:01,07:01
Class II
HLA-DQDQB1*02:02,02:02
HLA-DRDRB1*03:01,03:01
Disease Breast ductal carcinoma (NCIt: C4017)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Direct_author_submission; PubMed=20679594; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D1S165616
D2S44111
D2S133824,25
D3S135815
D5S81813
D7S8209
D8S117913
D10S124813
D12S39117,21
D13S3178
D16S53912
D18S5113
D19S43315,16.2
D21S1127,31.2
D22S104511,15
FGA20
Penta D11,13
Penta E12
TH016
TPOX8
vWA14,15

Run an STR similarity search on this cell line
Web pages Provider; UT Southwestern; -; https://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
Publications

PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084
Jessica Kao, Keyan Salari, Melanie Bocanegra, Yoon-La Choi, Luc Girard, Jeet Gandhi, Kevin A. Kwei, Tina Hernandez-Boussard, Pei Wang, Adi F. Gazdar, John D. Minna, Jonathan R. Pollack;
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.
PLoS ONE 4:e6146.1-e6146.16(2009)

PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474
Adi F. Gazdar, Luc Girard, William W. Lockwood, Wan L. Lam, John D. Minna;
Lung cancer cell lines as tools for biomedical discovery and research.
J. Natl. Cancer Inst. 102:1310-1321(2010)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_3376
DepMap; ACH-002323
Biological sample resources BioSample; SAMN03473199
Chemistry resources PharmacoDB; HCC2688_493_2019
Encyclopedic resources Wikidata; Q54881664
Experimental variables resources EFO; EFO_0006433
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM350545
Polymorphism and mutation databases Progenetix; CVCL_3376
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number22