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Cellosaurus HCN-2 (CVCL_3284)

[Text version]
Cell line name HCN-2
Synonyms HCN2; Human Cortical Neuronal cells-2
Accession CVCL_3284
Resource Identification Initiative To cite this cell line use: HCN-2 (RRID:CVCL_3284)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10742.
Senescence: The original stock from the patent deposition senesced at ~21 PDL, the one currently distributed has only 4-5 PDL remaining (ATCC=CRL-3592).
Doubling time: ~48 hours (PubMed=7700510).
Omics: Proteome analysis by 2D-DE/MS.
Derived from site: In situ; Brain, cerebral cortex; UBERON=UBERON_0000956.
Cell type: Neuron; CL=CL_0000540.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 7Y
Category Finite cell line
STR profile Source(s): ATCC=CRL-3592

Markers:
AmelogeninX
CSF1PO10,15
D5S81813
D7S8209,11
D13S31711,12
D16S5398,11
TH016,9.3
TPOX8
vWA14,20

Run an STR similarity search on this cell line
Web pages https://www.atcc.org/en/support/technical-support/faqs/atcc-normal-brain-cell-lines
Publications

Patent=US5196315
Ronnett G.V., Nye J.S., Hester L.D., Snyder S.H.
Human neuronal cell line.
Patent number US5196315, 23-Mar-1993

PubMed=7700510; DOI=10.1016/0306-4522(94)90574-6
Ronnett G.V., Hester L.D., Nye J.S., Snyder S.H.
Human cerebral cortical cell lines from patients with unilateral megalencephaly and Rasmussen's encephalitis.
Neuroscience 63:1081-1099(1994)

PubMed=14615026; DOI=10.1016/S0891-0618(03)00079-6
Peyrl A., Krapfenbauer K., Slavc I., Strobel T., Lubec G.
Proteomic characterization of the human cortical neuronal cell line HCN-2.
J. Chem. Neuroanat. 26:171-178(2003)

Cross-references
Cell line collections (Providers) ATCC; CRL-3592
ATCC; CRL-10742 - Discontinued
Cell line databases/resources CLO; CLO_0003664
Anatomy/cell type resources BTO; BTO_0003262
Biological sample resources BioSample; SAMN03471304
Encyclopedic resources Wikidata; Q54881896
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16