Cellosaurus cell line XR-V15B (CVCL

Cellosaurus XR-V15B (CVCL_3271)

Cross-references
Cell line name	XR-V15B
Synonyms	GM16144
Accession	CVCL_3271
Resource Identification Initiative	To cite this cell line use: XR-V15B (RRID:CVCL_3271)
Comments	Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU). Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations	Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line). Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line). Mutation; UniProtKB; Q60449; Xrcc5; Simple; p.Ala372_Glu417del46 (c.1114_1251del138); Zygosity=Unspecified (PubMed=8657125).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_6296 (V79B)
Sex of cell	Male
Age at sampling	Adult
Category	Transformed cell line
Publications	PubMed=2460764; DOI=10.1016/0167-8817(88)90025-9 Malgorzata Zofia Zdzienicka, Q. Tran, Govert Paulus van der Schans, Johannes W.I.M. Simons; Characterization of an X-ray-hypersensitive mutant of V79 Chinese hamster cells. Mutat. Res. 194:239-249(1988) PubMed=8657125; DOI=10.1128/mcb.16.4.1519; PMCID=PMC231136 Abdellatif Errami, Vaughn V. Smider, Wendy Kimryn Rathmell, Dong-Ming He, Eric A. Hendrickson, Malgorzata Zofia Zdzienicka, Gilbert Chu; Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Mol. Cell. Biol. 16:1519-1526(1996)
Cell line collections (Providers)	ATCC; CRL-2349 Coriell; GM16144 RCB; RCB2339
Cell line databases/resources	CLO; CLO_0009694 CLO; CLO_0018891 CLO; CLO_0051580
Encyclopedic resources	Wikidata; Q54995044
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	16