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Cellosaurus TCO-1 [Human cervical carcinoma] (CVCL_3179)

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Cell line name TCO-1 [Human cervical carcinoma]
Accession CVCL_3179
Resource Identification Initiative To cite this cell line use: TCO-1 [Human cervical carcinoma] (RRID:CVCL_3179)
Comments Problematic cell line: Contaminated. Shown to be a TCS derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a 34 year old patient with an uterine cervical adenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00272.
Population: Japanese.
Doubling time: 48 hours (PubMed=1607768).
Derived from site: Metastatic; Inguinal lymph node; UBERON=UBERON_0001542.
Disease Cervical keratinizing squamous cell carcinoma (NCIt: C40187)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8160 (TCS)
Sex of cell Female
Age at sampling 78Y
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=1607768
Hiroshi Fushiki;
Characterization of two novel cell lines established from a single human uterine cervical adenocarcinoma, and their chemosensitivities and hormonal effects on their proliferation.
Nihon Sanka Fujinka Gakkai Zasshi 44:397-404(1992)

PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x
Kaori Yoshino, Emi Iimura, Kaoru Saijo, Satsuki Iwase, Kiyoko Fukami, Tadao Ohno, Yuichi Obata, Yukio Nakamura;
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum. Cell 19:43-48(2006)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) RCB; RCB0640 - Discontinued
Biological sample resources BioSample; SAMN03151962
Chemistry resources ChEMBL-Cells; CHEMBL3308791
ChEMBL-Targets; CHEMBL1075599
PubChem_Cell_line; CVCL_3179
Encyclopedic resources Wikidata; Q54971889
Polymorphism and mutation databases Cosmic; 877475
Cosmic; 1152549
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23