• Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=7591257; PubMed=9738976).
  

PubMed=2513302; DOI=10.1111/j.1349-7006.1989.tb01727.x; PMCID=PMC5917846
Homma C., Kaneko Y., Sekine K.-i., Hara S.-i., Hata J.-i., Sakurai M.
Establishment and characterization of a small round cell sarcoma cell line, SCCH-196, with t(11;22)(q24;q12).
Jpn. J. Cancer Res. 80:861-865(1989)

PubMed=8221663
Komuro H., Hayashi Y., Kawamura M., Hayashi K., Kaneko Y., Kamoshita S., Hanada R., Yamamoto K., Hongo T., Yamada M., Tsuchida Y.
Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.
Cancer Res. 53:5284-5288(1993)

PubMed=7591257; DOI=10.1002/ijc.2910630407
Ida K., Kobayashi S., Taki T., Hanada R., Bessho F., Yamamori S., Sugimoto T., Ohki M., Hayashi Y.
EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor.
Int. J. Cancer 63:500-504(1995)

PubMed=9738976; DOI=10.1111/j.1349-7006.1998.tb03274.x; PMCID=PMC5921883
Urano F., Umezawa A., Yabe H., Hong W., Yoshida K., Fujinaga K., Hata J.-i.
Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosis.
Jpn. J. Cancer Res. 89:703-711(1998)

PubMed=12054564; DOI=10.1016/S0006-291X(02)00129-8
Yabe H., Fukuma M., Urano F., Yoshida K., Kato S., Toyama Y., Hata J.-i., Umezawa A.
Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of accessibility of the MMP regulatory element to the specific fusion protein in vivo.
Biochem. Biophys. Res. Commun. 293:61-71(2002)