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Cellosaurus RMUG-L (CVCL_3157)

[Text version]
Cell line name RMUG-L
Synonyms RMUGL
Accession CVCL_3157
Resource Identification Initiative To cite this cell line use: RMUG-L (RRID:CVCL_3157)
Comments Problematic cell line: Contaminated. Shown to be a SNG-II derivative. Originally thought to originate from a 62 year old female patient with an ovarian mucinous cystadenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00421.
Population: Japanese.
Doubling time: 53 hours (PubMed=2083224).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3170 (SNG-II)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): JCRB=IFO50319

Markers:
AmelogeninX
CSF1PO11,13
D5S8186,12,13
D7S8208,9,12
D13S3178,9,11
D16S53912,13,14
TH019
TPOX11
vWA15,16,17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2083224
Motoko Sakayori, Shiro Nozawa, Yasuhiro Udagawa, Keiko Chin, Soon-Gone Lee, Tatsuro Sakuma, Rihachi Iizuka, Yoriko Wada, Shigeko Yoshida, Yoshihiko Takeda;
Biological properties of two newly established cell lines (RMUG-S, RMUG-L) from a human ovarian mucinous cystadenocarcinoma.
Hum. Cell 3:52-56(1990)

CLPUB00481
Haruhiko Kuno, Touho Yoshida;
Detection of human papillomavirus types 16, 18, and 33 in cell lines derived from human genital organs by polymerase chain reaction.
Res. Commun. Inst. Ferment. 18:6-12(1997)

PubMed=11330945; DOI=10.1006/gyno.2001.6132
Takafumi Watanabe, Issei Imoto, Yoshinori Kosugi, Isamu Ishiwata, Satoshi Inoue, Masaomi Takayama, Akira Sato, Johji Inazawa;
A novel amplification at 17q21-23 in ovarian cancer cell lines detected by comparative genomic hybridization.
Gynecol. Oncol. 81:172-177(2001)

PubMed=12417041; DOI=10.1111/j.1349-7006.2002.tb01213.x; PMCID=PMC5926887
Takafumi Watanabe, Issei Imoto, Tomoyuki Katahira, Akira Hirasawa, Isamu Ishiwata, Mitsuru Emi, Masaomi Takayama, Akira Sato, Johji Inazawa;
Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers.
Jpn. J. Cancer Res. 93:1114-1122(2002)

PubMed=17671176; DOI=10.1158/0008-5472.CAN-06-4567
Ryoko Kikuchi, Hitoshi Tsuda, Yae Kanai, Takahiro Kasamatsu, Kazuo Sengoku, Setsuo Hirohashi, Johji Inazawa, Issei Imoto;
Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.
Cancer Res. 67:7095-7105(2007)

PubMed=19154404; DOI=10.1111/j.1349-7006.2008.01065.x; PMCID=PMC11159961
Seiya Sato, Hiroaki Itamochi, Junzo Kigawa, Tetsuro Oishi, Muneaki Shimada, Shinya Sato, Jun Naniwa, Kazunori Uegaki, Michiko Nonaka, Naoki Terakawa;
Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: a potential treatment strategy.
Cancer Sci. 100:546-551(2009)

PubMed=22246397; DOI=10.3892/or.2012.1626
Naoto Sato, Yasushi Saga, Hiroaki Mizukami, Dong-Dong Wang, Hiroyuki Fujiwara, Yuji Takei, Shizuo Machida, Keiya Ozawa, Mitsuaki Suzuki;
Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations.
Oncol. Rep. 27:1336-1340(2012)

Cross-references
Cell line collections (Providers) JCRB; IFO50319 - Discontinued
Cell line databases/resources CGH-DB; 346-2
CGH-DB; 9364-4
Biological sample resources BioSample; SAMN03151923
BioSample; SAMN03472785
Encyclopedic resources Wikidata; Q54950734
Gene expression databases GEO; GSM1001421
GEO; GSM1001422
Polymorphism and mutation databases Cosmic; 2429303
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23