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Cellosaurus RMUG-L (CVCL_3157)

[Text version]
Cell line name RMUG-L
Synonyms RMUGL
Accession CVCL_3157
Resource Identification Initiative To cite this cell line use: RMUG-L (RRID:CVCL_3157)
Comments Problematic cell line: Contaminated. Shown to be a SNG-II derivative. Originally thought to originate from a 62 year old female patient with an ovarian mucinous cystadenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00421.
Population: Japanese.
Doubling time: 53 hours (PubMed=2083224).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3170 (SNG-II)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO11,13
D5S8186,12,13
D7S8208,9,12
D13S3178,9,11
D16S53912,13,14
TH019
TPOX11
vWA15,16,17

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=2083224
Sakayori M., Nozawa S., Udagawa Y., Chin K., Lee S.-G., Sakuma T., Iizuka R., Wada Y., Yoshida S., Takeda Y.
Biological properties of two newly established cell lines (RMUG-S, RMUG-L) from a human ovarian mucinous cystadenocarcinoma.
Hum. Cell 3:52-56(1990)

CLPUB00481
Kuno H., Yoshida T.
Detection of human papillomavirus types 16, 18, and 33 in cell lines derived from human genital organs by polymerase chain reaction.
Res. Commun. Inst. Ferment. Osaka 18:6-12(1997)

PubMed=11330945; DOI=10.1006/gyno.2001.6132
Watanabe T., Imoto I., Kosugi Y., Ishiwata I., Inoue S., Takayama M., Sato A., Inazawa J.
A novel amplification at 17q21-23 in ovarian cancer cell lines detected by comparative genomic hybridization.
Gynecol. Oncol. 81:172-177(2001)

PubMed=12417041; DOI=10.1111/j.1349-7006.2002.tb01213.x
Watanabe T., Imoto I., Katahira T., Hirasawa A., Ishiwata I., Emi M., Takayama M., Sato A., Inazawa J.
Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers.
Jpn. J. Cancer Res. 93:1114-1122(2002)

PubMed=17671176; DOI=10.1158/0008-5472.CAN-06-4567
Kikuchi R., Tsuda H., Kanai Y., Kasamatsu T., Sengoku K., Hirohashi S., Inazawa J., Imoto I.
Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.
Cancer Res. 67:7095-7105(2007)

PubMed=19154404; DOI=10.1111/j.1349-7006.2008.01065.x
Sato S., Itamochi H., Kigawa J., Oishi T., Shimada M., Sato S., Naniwa J., Uegaki K., Nonaka M., Terakawa N.
Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: a potential treatment strategy.
Cancer Sci. 100:546-551(2009)

PubMed=22246397; DOI=10.3892/or.2012.1626
Sato N., Saga Y., Mizukami H., Wang D., Fujiwara H., Takei Y., Machida S., Ozawa K., Suzuki M.
Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations.
Oncol. Rep. 27:1336-1340(2012)

Cross-references
Cell line collections (Providers) JCRB; IFO50319 - Discontinued
Cell line databases/resources CGH-DB; 346-2
CGH-DB; 9364-4
Biological sample resources BioSample; SAMN03151923
BioSample; SAMN03472785
Encyclopedic resources Wikidata; Q54950734
Gene expression databases GEO; GSM1001421
GEO; GSM1001422
Polymorphism and mutation databases Cosmic; 2429303
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number21