Cellosaurus cell line PALL-2 (CVCL

Cellosaurus PALL-2 (CVCL_3122)

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Cell line name

PALL-2

Synonyms

PALL2; Ph1-positive Acute Lymphoblastic Leukemia-2

Accession

CVCL_3122

Resource Identification Initiative

To cite this cell line use: PALL-2 (RRID:CVCL_3122)

Comments

Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=8428799; PubMed=10071072).
Mutation; HGNC; HGNC:12766; NSD2; Simple; p.His554Gln (c.1662C>G); ClinVar=VCV001680176; Zygosity=Heterozygous (PubMed=35124168).

Disease

Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

45Y

Category

Cancer cell line

STR profile

Source(s): JCRB=JCRB1345

Markers:

Amelogenin	X,Y
CSF1PO	10
D5S818	11,12
D7S820	8,11
D13S317	8
D16S539	9,10
TH01	7,9
TPOX	8
vWA	18,19

Publications

PubMed=8428799; DOI=10.1002/ijc.2910530318
Tatsushi Miyagi, Junko H. Ohyashiki, Kenji Yamato, Harold Phillip Koeffler, Isao Miyoshi;
Phenotypic and molecular analysis of Ph1-chromosome-positive acute lymphoblastic leukemia cell lines.
Int. J. Cancer 53:457-462(1993)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Hans Gunther Drexler, Roderick A.F. MacLeod, Cord C. Uphoff;
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Minori Tamai, Shin Kasai, Koshi Akahane, Thao Nguyen Thu, Keiko Kagami, Chiaki Komatsu, Masako Abe, Atsushi Watanabe, Kumiko Goi, Kunio Miyake, Toshiya Inaba ...Show all 17 authors... , Junko Takita, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto, Kanji Sugita, Takeshi Inukai; Show fewer authors
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references

Cell line collections (Providers)

JCRB; JCRB1345
JCRB; NIHS0546 - Discontinued

Cell line databases/resources

SKIP; SKIP000748

Encyclopedic resources

Wikidata; Q54937484

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number