• Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Cys420Arg (c.1258T>C); ClinVar=VCV000031945; Zygosity=Heterozygous (DepMap=ACH-000527).
  

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Establishment and characterization of human ovarian clear cell carcinoma cell line, OVISE.
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PubMed=17671176; DOI=10.1158/0008-5472.CAN-06-4567
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PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22705003; DOI=10.1016/j.humpath.2012.03.011
Munmun Rahman, Kentaro Nakayama, Mohammed Tanjimur Rahman, Naomi Nakayama, Masako Ishikawa, Atsuko Katagiri, Kouji Iida, Satoru Nakayama, Yoshiro Otsuki, Ie-Ming Shih, Kohji Miyazaki;
Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma.
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PubMed=23839242; DOI=10.1038/ncomms3126; PMCID=PMC3715866
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Evaluating cell lines as tumour models by comparison of genomic profiles.
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PubMed=24023729; DOI=10.1371/journal.pone.0072162; PMCID=PMC3762837
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PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652
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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035.1-140035.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
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PubMed=25877200; DOI=10.1038/nature14397
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A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26388441; DOI=10.1016/j.cell.2015.08.056; PMCID=PMC4644236
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Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.
Cell 163:202-217(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
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PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008
Yusuke Masuishi, Yayoi Kimura, Noriaki Arakawa, Hisashi Hirano;
Identification of glycosylphosphatidylinositol-anchored proteins and omega-sites using TiO2-based affinity purification followed by hydrogen fluoride treatment.
J. Proteomics 139:77-83(2016)

PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930
Yusuke Masuishi, Yayoi Kimura, Noriaki Arakawa, Hisashi Hirano;
Data for identification of GPI-anchored peptides and omega-sites in cancer cell lines.
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PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
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A landscape of pharmacogenomic interactions in cancer.
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PubMed=27561551; DOI=10.1038/ncomms12645; PMCID=PMC5007461
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Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
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PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
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Characterization of human cancer cell lines by reverse-phase protein arrays.
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PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096; PMCID=PMC6481945
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Integrated genomic, epigenomic, and expression analyses of ovarian cancer cell lines.
Cell Rep. 25:2617-2633(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Fiona M. Behan, Francesco Iorio, Gabriele Picco, Emanuel Goncalves, Charlotte M. Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli, Rizwan Ansari ...Show all 25 authors... , Sarah Harper, David Adam Jackson, Rebecca McRae, Rachel Pooley, Piers Wilkinson, Dieudonne J. van der Meer, David Dow, Carolyn A. Buser-Doepner, Andrea Bertotti, Livio Trusolino, Euan Alexander Stronach, Julio Saez-Rodriguez, Kosuke Yusa, Mathew J. Garnett; Show fewer authors
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

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