• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys164Ter (c.490A>T); ClinVar=VCV000935480; Zygosity=Homozygous (Cosmic-CLP=1298362; DepMap=ACH-001625).
  

DOI=10.15114/tr.23.43
Toshikazu Yokoi, Akira Yamaguchi, Tetsuyo Odajima, Kazunori Furukawa;
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Tumor Res. 23:43-57(1989)

DOI=10.15114/tr.24.57
Toshikazu Yokoi, Hisato Homma, Tetsuyo Odajima;
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Tumor Res. 35:25-33(2000)

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J. Transl. Med. 7:1.1-1.11(2009)

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S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
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