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Cellosaurus NOMO-1/ADM (CVCL_3077)

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Cell line name NOMO-1/ADM
Accession CVCL_3077
Resource Identification Initiative To cite this cell line use: NOMO-1/ADM (RRID:CVCL_3077)
Comments Population: Japanese.
Doubling time: ~1.5 days (Note=Lot 10032003) (JCRB=JCRB1069).
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; HGNC:3373; EP300; Simple; c.730-10T>C; ClinVar=VCV003011970; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys242Alafs*5 (c.723delC) (p.S241fs); ClinVar=VCV001074338; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1609 (NOMO-1)
Sex of cell Female
Age at sampling 31Y
Category Cancer cell line
Publications

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) JCRB; JCRB1069
Cell line databases/resources CLO; CLO_0009852
cancercelllines; CVCL_3077
LINCS_LDP; LCL-1064
Encyclopedic resources Wikidata; Q54930899
Gene expression databases GEO; GSM827275
Polymorphism and mutation databases Progenetix; CVCL_3077
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number26