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Cellosaurus NCC-RbC-51 (CVCL_3048)

[Text version]
Cell line name NCC-RbC-51
Synonyms NCC-RBC-51; NCC-RbC-R51; R51
Accession CVCL_3048
Resource Identification Initiative To cite this cell line use: NCC-RbC-51 (RRID:CVCL_3048)
Comments Population: Japanese.
Doubling time: 85 hours (PubMed=8263010); 67 hours (PubMed=31781967).
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Gene deletion; HGNC; HGNC:9884; RB1; Zygosity=Heterozygous (PubMed=31781967).
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex24del; Zygosity=Heterozygous (PubMed=31781967).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 4Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1182; RCB=RCB2206

Markers:
AmelogeninX,Y
CSF1PO13
D5S81810
D7S82012
D13S31711,12
D16S53910,12
TH019
TPOX9,11
vWA14

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Publications

PubMed=8263010; DOI=10.1007/BF01202193
Motoko Inomata, Akihiro Kaneko, Nagahiro Saijo, Seiichi Tokura;
Culture of retinoblastoma cells from clinical specimens: growth-promoting effect of 2-mercaptoethanol.
J. Cancer Res. Clin. Oncol. 120:149-155(1994)

PubMed=7499444; DOI=10.1007/BF01213319
Motoko Inomata, Nagahiro Saijo, Kazuko Kawashima, Akihiro Kaneko, Yasuhiro Fujiwara, Hiroshi Kunikane, Yasuhiko Tanaka;
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
J. Cancer Res. Clin. Oncol. 121:729-738(1995)

PubMed=12406979; DOI=10.1093/clinchem/48.11.1938
Masato Maekawa, Motoko Inomata, Masao S. Sasaki, Akihiro Kaneko, Mineko Ushiama, Kenshi Sugano, Jun Takayama, Takashi Kanno;
Electrophoretic variant of a lactate dehydrogenase isoenzyme and selective promoter methylation of the LDHA gene in a human retinoblastoma cell line.
Clin. Chem. 48:1938-1945(2002)

PubMed=31781967; DOI=10.1007/s00418-019-01832-1
Hemanth Ravishankar, Abubakar Siddiq Mangani, M. Bhavani Shankar, Mayur Joshi, Thiyagarajan Devasena, Sowmya Parameswaran, Krishnakumar Subramaniam;
Characterization of NCC-RbC-51, an RB cell line isolated from a metastatic site.
Histochem. Cell Biol. 153:101-109(2020)

Cross-references
Cell line collections (Providers) JCRB; JCRB1182
RCB; RCB2206
Cell line databases/resources CLO; CLO_0050135
Biological sample resources BioSample; SAMN01821705
BioSample; SAMN03472423
Encyclopedic resources Wikidata; Q54907620
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17