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Cellosaurus NCC-RbC-51 (CVCL_3048)

[Text version]
Cell line name NCC-RbC-51
Synonyms NCC-RBC-51; NCC-RbC-R51; R51
Accession CVCL_3048
Resource Identification Initiative To cite this cell line use: NCC-RbC-51 (RRID:CVCL_3048)
Comments Population: Japanese.
Doubling time: 85 hours (PubMed=8263010); 67 hours (PubMed=31781967).
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Gene deletion; HGNC; 9884; RB1; Zygosity=Heterozygous (PubMed=31781967).
  • Mutation; HGNC; 9884; RB1; Unexplicit; Ex24del; Zygosity=Heterozygous (PubMed=31781967).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 4Y
Category Cancer cell line
STR profile Source(s): JCRB; RCB


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PubMed=8263010; DOI=10.1007/BF01202193
Inomata M., Kaneko A., Saijo N., Tokura S.
Culture of retinoblastoma cells from clinical specimens: growth-promoting effect of 2-mercaptoethanol.
J. Cancer Res. Clin. Oncol. 120:149-155(1994)

PubMed=7499444; DOI=10.1007/BF01213319
Inomata M., Saijo N., Kawashima K., Kaneko A., Fujiwara Y., Kunikane H., Tanaka Y.
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
J. Cancer Res. Clin. Oncol. 121:729-738(1995)

PubMed=12406979; DOI=10.1093/clinchem/48.11.1938
Maekawa M., Inomata M., Sasaki M.S., Kaneko A., Ushiama M., Sugano K., Takayama J., Kanno T.
Electrophoretic variant of a lactate dehydrogenase isoenzyme and selective promoter methylation of the LDHA gene in a human retinoblastoma cell line.
Clin. Chem. 48:1938-1945(2002)

PubMed=31781967; DOI=10.1007/s00418-019-01832-1
Ravishankar H., Mangani A.S., Shankar M.B., Joshi M., Devasena T., Parameswaran S., Subramaniam K.
Characterization of NCC-RbC-51, an RB cell line isolated from a metastatic site.
Histochem. Cell Biol. 153:101-109(2020)

Cell line collections (Providers) JCRB; JCRB1182
RCB; RCB2206
Cell line databases/resources CLO; CLO_0050135
Biological sample resources BioSample; SAMN01821705
BioSample; SAMN03472423
Encyclopedic resources Wikidata; Q54907620
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number15