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Cellosaurus MEG-01SSF (CVCL_3023)

[Text version]
Cell line name MEG-01SSF
Synonyms MEG-01sSF; MEG-01s Serum Free
Accession CVCL_3023
Resource Identification Initiative To cite this cell line use: MEG-01SSF (RRID:CVCL_3023)
Comments Group: Serum/protein free medium cell line.
Population: Japanese.
Doubling time: ~20 hours (PubMed=1367286).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:18318; ASXL1; Simple; p.Gly646Trpfs*12 (c.1934dupG); ClinVar=VCV000426927; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His233del (c.697_699delCAC); Zygosity=Heterozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3022 (MEG-01s)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): JCRB=IFO50294

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81813
D7S82011
D13S3178
D16S5399
TH017,8
TPOX8,11
vWA16

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Publications

PubMed=1367286
Masao Takeuchi, Motonobu Satoh, Michinori Ogura, Hidehiko Saito, Kikuko Takeuchi;
Properties of a cell line (MEG-01SSF) of human megakaryoblastic leukemia cells.
Res. Commun. Inst. Ferment. 15:22-29(1991)

Cross-references
Cell line collections (Providers) JCRB; IFO50294
Encyclopedic resources Wikidata; Q54905037
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20