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Cellosaurus Lu-65B (CVCL_3013)

[Text version]
Cell line name Lu-65B
Synonyms LU-65B; LU65B
Accession CVCL_3013
Resource Identification Initiative To cite this cell line use: Lu-65B (RRID:CVCL_3013)
Comments Population: Japanese.
Omics: SNP array analysis.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Ser82Ter (c.245C>A); ClinVar=VCV000837710; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu11Gln (c.31G>C); ClinVar=VCV000041723; Zygosity=Homozygous (from parent cell line).
Disease Lung giant cell carcinoma (NCIt: C4452)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1392 (Lu-65)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB0055


Run an STR similarity search on this cell line

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cell line collections (Providers) JCRB; JCRB0055
Cell line databases/resources CLO; CLO_0037026
cancercelllines; CVCL_3013
Encyclopedic resources Wikidata; Q54903208
Gene expression databases GEO; GSM827384
Polymorphism and mutation databases Progenetix; CVCL_3013
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number24