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Cellosaurus HEY-T30 (CVCL_2Z96)

[Text version]
Cell line name HEY-T30
Accession CVCL_2Z96
Resource Identification Initiative To cite this cell line use: HEY-T30 (RRID:CVCL_2Z96)
Comments Population: Caucasian.
Doubling time: ~18-22 hours (ATCC=CRL-3252).
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly464Glu (c.1391G>A); ClinVar=VCV000013964; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0297 (HEY)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3252

Markers:
AmelogeninX
CSF1PO10,11
D5S81811,12
D7S82012
D13S31711
D16S5398,12
TH018,9.3
TPOX11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=20404007; DOI=10.1158/1078-0432.CCR-09-3233; PMCID=PMC2887721
Gloria S. Huang, Jurriaan Brouwer-Visser, Marissa J. Ramirez, Christine H. Kim, Tiffany M. Hebert, Juan Lin, Hugo Arias-Pulido, Clifford R. Qualls, Eric R. Prossnitz, Gary L. Goldberg, Harriet O. Smith, Susan Band Horwitz;
Insulin-like growth factor 2 expression modulates taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer.
Clin. Cancer Res. 16:2999-3010(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-3252
Cell line databases/resources cancercelllines; CVCL_2Z96
Encyclopedic resources Wikidata; Q54883217
Entry history
Entry creation22-Sep-2015
Last entry update19-Dec-2024
Version number15