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Cellosaurus AG21158 (CVCL_2Y81)

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Cell line name AG21158
Accession CVCL_2Y81
Resource Identification Initiative To cite this cell line use: AG21158 (RRID:CVCL_2Y81)
Comments Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Arg176Cys (c.526C>T); ClinVar=VCV000017848; Zygosity=Heterozygous; Note=ApoE2 allele (Coriell=AG21158).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_YN67 (AG27607)
Originate from same individual CVCL_2Y82 ! AG21159
Sex of cell Female
Age at sampling 69Y
Category Finite cell line
Publications

PubMed=30699343; DOI=10.1016/j.celrep.2019.01.023; PMCID=PMC6386196
Katharina Meyer, Heather M. Feldman, Tao Lu, Derek Drake, Elaine Teng-Tim Lim, King-Hwa Ling, Nicholas A. Bishop, Ying Pan, Jinsoo Seo, Yuan-Ta Lin, Susan C. Su ...Show all 14 authors... , George McDonald Church, Li-Huei Tsai, Bruce A. Yankner; Show fewer authors
REST and neural gene network dysregulation in iPSC models of Alzheimer's disease.
Cell Rep. 26:1112-1127.e9(2019)

Cross-references
Cell line collections (Providers) Coriell; AG21158
Cell line databases/resources CLO; CLO_0011294
Encyclopedic resources Wikidata; Q54748137
Entry history
Entry creation22-Sep-2015
Last entry update19-Dec-2024
Version number13