Cellosaurus cell line AG04446 (CVCL

Cellosaurus AG04446 (CVCL_2A88)

Cross-references
Cell line name	AG04446
Synonyms	AG_04446; GRC#0246
Accession	CVCL_2A88
Resource Identification Initiative	To cite this cell line use: AG04446 (RRID:CVCL_2A88)
Comments	Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection. Population: Caucasian. Senescence: Senesces at 37 PDL (PubMed=9724752); 33 PDL (Coriell=AG04446). Doubling time: 2.2 days (PubMed=12840040). Omics: Transcriptomics; Microarray. Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427. Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_2E80 ! AG12851
Sex of cell	Male
Age at sampling	48Y
Category	Finite cell line
Publications	PubMed=7307581; DOI=10.1159/000131624 Edward L. Schneider, Robert Monticone, James R. Smith, Karen I. Braunschweiger, Thomas W. Roberts; Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging. Cytogenet. Cell Genet. 31:40-46(1981) CLPUB00597 National Institute on Aging 1994 catalog of cell lines. NIA Aging Cell Repository. (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994) PubMed=9724752; DOI=10.1073/pnas.95.18.10614; PMCID=PMC27943 Vincent J. Cristofalo, Robert G. Allen, Robert J. Pignolo, Bernard G. Martin, Jeanne C. Beck; Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation. Proc. Natl. Acad. Sci. U.S.A. 95:10614-10619(1998) PubMed=12840040; DOI=10.1101/gr.1289803; PMCID=PMC403735 Mazen W. Karaman, Marlys L. Houck, Leona G. Chemnick, Shailender Nagpal, Daniel Chawannakul, Dominick Sudano, Brian L. Pike, Vincent V. Ho, Oliver Allison Ryder, Joseph G. Hacia; Comparative analysis of gene-expression patterns in human and African great ape cultured fibroblasts. Genome Res. 13:1619-1630(2003)
Cell line collections (Providers)	Coriell; AG04446
Cell line databases/resources	CLO; CLO_0034835
Encyclopedic resources	Wikidata; Q54610236
Gene expression databases	GEO; GSM6347 GEO; GSM6386
Entry history
Entry creation	22-Sep-2015
Last entry update	10-Apr-2025
Version number	14