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Cellosaurus RYAS41 (CVCL_2A39)

[Text version]
Cell line name RYAS41
Synonyms Ryas 41
Accession CVCL_2A39
Resource Identification Initiative To cite this cell line use: RYAS41 (RRID:CVCL_2A39)
Comments Characteristics: Secretes insulin in response to glucose stimulation.
Characteristics: Has been transduced with a recombinant lentivirus expressing the SV40 T antigen under the control of the insulin promoter.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryonic pancreas, islets of Langerhans; UBERON=UBERON_0003921+UBERON_0000006.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.
Sex of cell Sex unspecified
Age at sampling 13FD
Category Transformed cell line
Publications

PubMed=19266046; DOI=10.1371/journal.pone.0004731; PMCID=PMC2649535
Ravassard P., Bricout-Neveu E., Hazhouz Y., Pechberty S., Mallet J., Czernichow P., Scharfmann R.
A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors.
PLoS ONE 4:e4731.1-e4731.9(2009)

Cross-references
Encyclopedic resources Wikidata; Q54951517
Entry history
Entry creation22-Sep-2015
Last entry update10-Apr-2025
Version number12