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Cellosaurus U-251MG (KO) (CVCL_2809)

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Cell line name U-251MG (KO)
Synonyms U-251 MG (KO)
Accession CVCL_2809
Resource Identification Initiative To cite this cell line use: U-251MG (KO) (RRID:CVCL_2809)
Comments Population: Caucasian.
Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0021 (U-251MG)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): JCRB=IFO50285

Markers:
AmelogeninX
CSF1PO11,12
D5S81811
D7S82010,12
D13S31710,11
D16S53912
TH019.3
TPOX8
vWA16,18

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Publications

PubMed=7763724
Motonobu Satoh, Masao Takeuchi;
Cross-contamination of cell lines as revealed by DNA fingerprinting in the IFO animal cell bank.
Res. Commun. Inst. Ferment. 16:18-23(1993)

Cross-references
Cell line collections (Providers) JCRB; IFO50285
Cell line databases/resources cancercelllines; CVCL_2809
Biological sample resources BioSample; SAMN03472772
Encyclopedic resources Wikidata; Q54973551
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22