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Cellosaurus HSC-1 (CVCL_2807)

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Cell line name HSC-1
Synonyms HSC1; HSC-I
Accession CVCL_2807
Resource Identification Initiative To cite this cell line use: HSC-1 (RRID:CVCL_2807)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Hand, skin; UBERON=UBERON_0001519.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Phe (c.404G>T); ClinVar=VCV000376559; Zygosity=Unspecified (DepMap=ACH-001523).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val173Leu (c.517G>T); ClinVar=VCV000376668; Zygosity=Unspecified (DepMap=ACH-001523).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_JG49 (HSC-1-Luc)
Originate from same individual CVCL_M669 ! HSC-1b
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001523; JCRB=JCRB1015; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO12,13
D2S133819
D3S135816
D5S81810,13
D7S82011,12
D8S117912,14
D13S31711,12
D16S53911,12
D18S5121
D19S43312.2,13
D21S1130
FGA20
Penta D9
Penta E5,17
TH017
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=7284243; DOI=10.1111/j.1365-2133.1981.tb01196.x
Shigeo Kondo, Kazuo Aso;
Establishment of a cell line of human skin squamous cell carcinoma in vitro.
Br. J. Dermatol. 105:125-132(1981)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1015
JCRB; NIHS0249 - Discontinued
Cell line databases/resources cancercelllines; CVCL_2807
Cell_Model_Passport; SIDM01557
DepMap; ACH-001523
Anatomy/cell type resources BTO; BTO_0005167
Biological sample resources BioSample; SAMN03470890
Encyclopedic resources Wikidata; Q54896379
Polymorphism and mutation databases IARC_TP53; 26921
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23