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Cellosaurus UM-UC-5 (CVCL_2750)

[Text version]
Cell line name UM-UC-5
Synonyms UMUC5; University of Michigan-Urothelial Carcinoma-5
Accession CVCL_2750
Resource Identification Initiative To cite this cell line use: UM-UC-5 (RRID:CVCL_2750)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: UBC-40 urothelial bladder cancer cell line index.
Doubling time: 19 hours (PubMed=3761468).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp53Ter (c.159G>A); ClinVar=VCV000420659; Zygosity=Unspecified (DepMap=ACH-001411).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001411; ECACC=08090502

Markers:
AmelogeninX
CSF1PO11
D3S135815
D5S81813
D7S82010,12
D8S117912,13
D13S3178,12
D16S53911,13
D18S5113,16
D21S1132.2
FGA20
Penta D9
Penta E15,17
TH017,9
TPOX9,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=3761468; DOI=10.1016/S0022-5347(17)45139-1
Herbert Barton Grossman, Gary Wedemeyer, Li-Qin Ren, Golder N. Wilson, Beth Cox;
Improved growth of human urothelial carcinoma cell cultures.
J. Urol. 136:953-959(1986)

PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052
Yves Allory, Willemien Beukers, Ana Sagrera, Marta Flandez, Miriam Marques, Mirari Marquez, Kirstin A. van der Keur, Lars Dyrskjot, Irene Lurkin, Marcel Vermeij, Alfredo Carrato ...Show all 24 authors... , Josep Lloreta, Jose A. Lorente, Enrique Carrillo-de-Santa-Pau, Roy G. Masius, Manolis Kogevinas, Ewout Willem Steyerberg, Angela A.G. van Tilborg, Cheno Abas, Torben Falck Orntoft, Tahlita C.M. Zuiverloon, Nuria Malats, Ellen C. Zwarthoff, Francisco X. Real; Show fewer authors
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.
Eur. Urol. 65:360-366(2014)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036
Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau, Benjamin Rodriguez-Santiago, Marinela Mendez-Pertuz, Herbert Auer, Gonzalo Gomez, Herbert Barton Grossman, David G. Pisano, Wolfgang A. Schulz, Luis A. Perez-Jurado ...Show all 16 authors... , Alfredo Carrato, Dan Theodorescu, Stephen Jacob Chanock, Alfonso Valencia, Francisco X. Real; Show fewer authors
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) CancerTools; 160437
ECACC; 08090502
Cell line databases/resources cancercelllines; CVCL_2750
Cell_Model_Passport; SIDM01909
DepMap; ACH-001411
Anatomy/cell type resources BTO; BTO_0004993
Encyclopedic resources Wikidata; Q54990992
Gene expression databases GEO; GSM1567863
GEO; GSM1574558
Polymorphism and mutation databases Cosmic; 1082648
Cosmic; 1938702
Cosmic; 2037969
Cosmic; 2700983
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29