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Cellosaurus UM-UC-11 (CVCL_2745)

[Text version]
Cell line name UM-UC-11
Synonyms UM-UC11; UMUC11; UC-11; University of Michigan-Urothelial Carcinoma-11
Accession CVCL_2745
Resource Identification Initiative To cite this cell line use: UM-UC-11 (RRID:CVCL_2745)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: UBC-40 urothelial bladder cancer cell line index.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001413; ECACC=08090507

Markers:
AmelogeninX,Y
CSF1PO10
D3S135815,16
D5S81812
D7S8208,12
D8S117911,13
D13S31711,14
D16S53911
D18S5113
D21S1130
FGA20,23
Penta D11,13
Penta E7,10
TH016,9
TPOX9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=16469639; DOI=10.1016/S0022-5347(05)00323-X
Anita Lyn Sabichi, Afsaneh Keyhani, Noriyoshi Tanaka, Jorge Delacerda, I-Ling Lee, Chang-Ping Zou, Jian-Hua Zhou, William F. Benedict, Herbert Barton Grossman;
Characterization of a panel of cell lines derived from urothelial neoplasms: genetic alterations, growth in vivo and the relationship of adenoviral mediated gene transfer to coxsackie adenovirus receptor expression.
J. Urol. 175:1133-1137(2006)

PubMed=18812553; DOI=10.1093/jnci/djn304; PMCID=PMC2720731
Hong-Seok Park, Weon Seo Park, Jolanta Bondaruk, Noriyoshi Tanaka, Hiroshi Katayama, Sangkyou Lee, Philippe E. Spiess, Jordan R. Steinberg, Zhi Wang, Ruth L. Katz, Colin Padraic Neal Dinney ...Show all 18 authors... , Keren J. Elias, Yair Lotan, Rizwan C. Naeem, Keith Baggerly, Subrata Sen, Herbert Barton Grossman, Bogdan Czerniak; Show fewer authors
Quantitation of Aurora kinase A gene copy number in urine sediments and bladder cancer detection.
J. Natl. Cancer Inst. 100:1401-1411(2008)

PubMed=19375735; DOI=10.1016/j.juro.2009.01.108; PMCID=PMC2680455
Edmund Chiong, Ali Dadbin, Loleta D. Harris, Anita Lyn Sabichi, Herbert Barton Grossman;
The use of short tandem repeat profiling to characterize human bladder cancer cell lines.
J. Urol. 181:2737-2748(2009)

PubMed=23401075; DOI=10.1002/path.4176
Ya-Nan Guo, Yvonne Chekaluk, Jian-Ming Zhang, Jin-Yan Du, Nathanael S. Gray, Chin-Lee Wu, David Joseph Kwiatkowski;
TSC1 involvement in bladder cancer: diverse effects and therapeutic implications.
J. Pathol. 230:17-27(2013)

PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052
Yves Allory, Willemien Beukers, Ana Sagrera, Marta Flandez, Miriam Marques, Mirari Marquez, Kirstin A. van der Keur, Lars Dyrskjot, Irene Lurkin, Marcel Vermeij, Alfredo Carrato ...Show all 24 authors... , Josep Lloreta, Jose A. Lorente, Enrique Carrillo-de-Santa-Pau, Roy G. Masius, Manolis Kogevinas, Ewout Willem Steyerberg, Angela A.G. van Tilborg, Cheno Abas, Torben Falck Orntoft, Tahlita C.M. Zuiverloon, Nuria Malats, Ellen C. Zwarthoff, Francisco X. Real; Show fewer authors
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.
Eur. Urol. 65:360-366(2014)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036
Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau, Benjamin Rodriguez-Santiago, Marinela Mendez-Pertuz, Herbert Auer, Gonzalo Gomez, Herbert Barton Grossman, David G. Pisano, Wolfgang A. Schulz, Luis A. Perez-Jurado ...Show all 16 authors... , Alfredo Carrato, Dan Theodorescu, Stephen Jacob Chanock, Alfonso Valencia, Francisco X. Real; Show fewer authors
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) CancerTools; 160441
ECACC; 08090507 - Discontinued
Cell line databases/resources Cell_Model_Passport; SIDM01407
DepMap; ACH-001413
Encyclopedic resources Wikidata; Q54990973
Gene expression databases GEO; GSM1567858
GEO; GSM1574591
Polymorphism and mutation databases Cosmic; 846279
Cosmic; 1927298
Cosmic; 1938706
Cosmic; 2037963
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27