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Cellosaurus UM-RC-7 (CVCL_2742)

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Cell line name UM-RC-7
Synonyms UMRC-7; UMRC7; University of Michigan-Renal Carcinoma-7
Accession CVCL_2742
Resource Identification Initiative To cite this cell line use: UM-RC-7 (RRID:CVCL_2742)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~53 hours (PubMed=4038766).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Pro61Alafs*61 (c.180_208del); Zygosity=Unspecified (PubMed=7915601).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001688; ECACC=08090514; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,25
D3S135815
D5S81812
D7S82010
D8S117913,14
D13S3178,11
D16S53911
D18S5113,14,19 (PubMed=25877200)
14,19 (DepMap=ACH-001688)
D19S43314,15,16.2
D21S1131.2,33.2
FGA24,25
Penta D9,12
Penta E7,9
TH018,9
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=4038766; DOI=10.1002/jso.2930280320
Herbert Barton Grossman, Gary Wedemeyer, Li-Qin Ren;
Human renal carcinoma: characterization of five new cell lines.
J. Surg. Oncol. 28:237-244(1985)

PubMed=7915601; DOI=10.1038/ng0594-85
James R. Gnarra, Kalman Tory, Yong-Kai Weng, Laura S. Schmidt, Ming Hui Wei, Hua Li, Farida Latif, Sue Liu, Fan Chen, Fuh-Mei Duh, Irina A. Lubensky ...Show all 24 authors... , Dah-Shuhn R. Duan, Charles Florence, Rudy Pozzatti, McClellan Milton Walther, Neil Harrison Bander, Herbert Barton Grossman, Hiltrud Brauch, Sigmund Pomer, James D. Brooks, William B. Isaacs, Michael I. Lerman, Berton Zbar, William Marston Linehan; Show fewer authors
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) CancerTools; 160449
ECACC; 08090514 - Discontinued
Ximbio; 160449
Cell line databases/resources DepMap; ACH-001688
Biological sample resources BioSample; SAMN03470957
Encyclopedic resources Wikidata; Q54990788
Polymorphism and mutation databases Cosmic; 972914
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20