Cellosaurus cell line TOU (TOU I-2) (CVCL

Cellosaurus TOU (TOU I-2) (CVCL_2735)

Cross-references
Cell line name	TOU (TOU I-2)
Synonyms	TOU; TOU I-2
Accession	CVCL_2735
Resource Identification Initiative	To cite this cell line use: TOU (TOU I-2) (RRID:CVCL_2735)
Comments	Population: Tunisian; Berber. Characteristics: Heterozygous for deletion of IGH G1-EP1-A1-GP-G2-G4 and of EP1-A1-GP. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene deletion; HGNC; HGNC:5478; IGHA1; Zygosity=Homozygous (PubMed=6438434). Gene deletion; HGNC; HGNC:5523; IGHEP1; Zygosity=Homozygous (PubMed=6438434). Gene deletion; HGNC; HGNC:5525; IGHG1; Zygosity=Heterozygous (PubMed=6438434). Gene deletion; HGNC; HGNC:5526; IGHG2; Zygosity=Heterozygous (PubMed=6438434). Gene deletion; HGNC; HGNC:5528; IGHG4; Zygosity=Heterozygous (PubMed=6438434). Gene deletion; HGNC; HGNC:5529; IGHGP; Zygosity=Homozygous (PubMed=6438434).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Category	Transformed cell line
Web pages	Info; IMGT; -; https://www.imgt.org/IMGTrepertoire/LocusGenes/locus/human/IGH/Hu_IGHcellines.html
Publications	PubMed=6438434 Marie-Paule Lefranc, Gerard Lefranc, Gerda de Lange, Theo A. Out, Peter J. van den Broek, Janny van Nieuwkoop, Jiri Radl, Ahmed N. Helal, Hassen Chaabani, Erna van Loghem, Terence Howard Rabbitts; Instability of the human immunoglobulin heavy chain constant region locus indicated by different inherited chromosomal deletions. Mol. Biol. Med. 1:207-217(1983)
Cell line collections (Providers)	ECACC; 93093001
Cell line databases/resources	CLO; CLO_0009383 CLDB; cl4536
Encyclopedic resources	Wikidata; Q54972792
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	14