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Cellosaurus PE/CA-PJ41 (clone D2) (CVCL_2680)

[Text version]
Cell line name PE/CA-PJ41 (clone D2)
Synonyms PECAPJ41CLONED2; PE-CA-PJ41-cl D2; PE/CA-PJ-41; PE CA PJ41; PECAPJ41; Plaepi 41
Accession CVCL_2680
Resource Identification Initiative To cite this cell line use: PE/CA-PJ41 (clone D2) (RRID:CVCL_2680)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: KuDOS 95 cell line panel.
Population: Caucasian.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Misspelling: PECAPJ34CLONED2; GEO=GSM1374830.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.920-2A>T (IVS8-2A>T); ClinVar=VCV002461841; Zygosity=Homozygous; Note=Splice acceptor mutation (DepMap=ACH-000732).
Genome ancestry Source: PubMed=30894373

Origin% genome
African2.91
Native American0
East Asian, North3.3
East Asian, South0
South Asian0
European, North62.2
European, South31.58
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): ECACC=98020207

Markers:
AmelogeninX
CSF1PO11,13
D5S81812
D7S8209,11
D13S31711,12
D16S53911,13
TH017
TPOX8
vWA15,19

Run an STR similarity search on this cell line
Publications

PubMed=9876219
Alexander Berndt, Peter Hyckel, Annett Konneker, Detlef Katenkamp, Hartwig Kosmehl;
Oral squamous cell carcinoma invasion is associated with a laminin-5 matrix re-organization but independent of basement membrane and hemidesmosome formation. Clues from an in vitro invasion model.
Invasion Metastasis 17:251-258(1997)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) ECACC; 98020207
Cell line databases/resources CLO; CLO_0008409
cancercelllines; CVCL_2680
Cell_Model_Passport; SIDM01323
DepMap; ACH-000732
Biological sample resources BioSample; SAMN10988012
Chemistry resources PharmacoDB; PE_CAPJ41_cloneD2_1258_2019
Encyclopedic resources Wikidata; Q54946884
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887510
GEO; GSM888592
GEO; GSM1374830
GEO; GSM1374831
Polymorphism and mutation databases Cosmic; 1339922
IARC_TP53; 28261
LiGeA; CCLE_664
Progenetix; CVCL_2680
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29