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Cellosaurus P4E6 (CVCL_2677)

[Text version]
Cell line name P4E6
Accession CVCL_2677
Resource Identification Initiative To cite this cell line use: P4E6 (RRID:CVCL_2677)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): DepMap=ACH-001627; ECACC=10112301

Markers:
AmelogeninX
CSF1PO12
D3S135816,17
D5S81812
D7S8207,8
D8S117910,14
D13S31711
D16S53911
D18S5116,18
D21S1127,30.2
FGA25
Penta D9,12
Penta E11
TH017,9.3
TPOX8
vWA17,19

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Publications

PubMed=11121225; DOI=10.1667/0033-7587(2001)155[0133:IVMTSC]2.0.CO;2
Norman J. Maitland, Catherine A. Macintosh, June Hall, Mike Sharrard, Gary Quinn, Shona H. Lang;
In vitro models to study cellular differentiation and function in human prostate cancers.
Radiat. Res. 155:133-142(2001)

PubMed=17163777; DOI=10.1290/0511080.1
Shona H. Lang, Joel Smith, Catherine Hyde, Catherine A. Macintosh, Michael Stower, Norman J. Maitland;
Differentiation of prostate epithelial cell cultures by matrigel/ stromal cell glandular reconstruction.
In Vitro Cell. Dev. Biol. Anim. 42:273-280(2006)

PubMed=28094783; DOI=10.1038/srep40633; PMCID=PMC5240554
Naomi Harner-Foreman, Jayakumar Vadakekolathu, Stephanie A. Laversin, Morgan G. Mathieu, Stephen Reeder, A. Graham Pockley, Robert C. Rees, David J. Boocock;
A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics.
Sci. Rep. 7:40633-40633(2017)

Cross-references
Cell line collections (Providers) ECACC; 10112301
Cell line databases/resources DepMap; ACH-001627
Anatomy/cell type resources BTO; BTO_0003540
Encyclopedic resources Wikidata; Q54937297
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number21