Cellosaurus cell line P4E6 (CVCL

Cellosaurus P4E6 (CVCL_2677)

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Cell line name

P4E6

Accession

CVCL_2677

Resource Identification Initiative

To cite this cell line use: P4E6 (RRID:CVCL_2677)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.

Disease

Prostate carcinoma (NCIt: C4863)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

Age unspecified

Category

Transformed cell line

STR profile

Source(s): DepMap=ACH-001627; ECACC=10112301

Markers:

Amelogenin	X
CSF1PO	12
D3S1358	16,17
D5S818	12
D7S820	7,8
D8S1179	10,14
D13S317	11
D16S539	11
D18S51	16,18
D21S11	27,30.2
FGA	25
Penta D	9,12
Penta E	11
TH01	7,9.3
TPOX	8
vWA	17,19

Publications

PubMed=11121225; DOI=10.1667/0033-7587(2001)155[0133:IVMTSC]2.0.CO;2
Norman J. Maitland, Catherine A. Macintosh, June Hall, Mike Sharrard, Gary Quinn, Shona H. Lang;
In vitro models to study cellular differentiation and function in human prostate cancers.
Radiat. Res. 155:133-142(2001)

PubMed=17163777; DOI=10.1290/0511080.1
Shona H. Lang, Joel Smith, Catherine Hyde, Catherine A. Macintosh, Michael Stower, Norman J. Maitland;
Differentiation of prostate epithelial cell cultures by matrigel/ stromal cell glandular reconstruction.
In Vitro Cell. Dev. Biol. Anim. 42:273-280(2006)

PubMed=28094783; DOI=10.1038/srep40633; PMCID=PMC5240554
Naomi Harner-Foreman, Jayakumar Vadakekolathu, Stephanie A. Laversin, Morgan G. Mathieu, Stephen Reeder, A. Graham Pockley, Robert C. Rees, David J. Boocock;
A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics.
Sci. Rep. 7:40633.1-40633.18(2017)

Cross-references

Cell line collections (Providers)

ECACC; 10112301

Cell line databases/resources

DepMap; ACH-001627

Anatomy/cell type resources

BTO; BTO_0003540

Encyclopedic resources

Wikidata; Q54937297

Entry history

Entry creation

04-Apr-2012

Last entry update

14-Aug-2025

Version number