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Cellosaurus N-thy-ts.1 (CVCL_2660)

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Cell line name N-thy-ts.1
Synonyms Nthy-ts1; ts.1
Accession CVCL_2660
Resource Identification Initiative To cite this cell line use: N-thy-ts.1 (RRID:CVCL_2660)
Comments Characteristics: Grows at the permissive temperature (33 Celsius), but not at the restrictive temperature (40.5 Celsius).
Doubling time: ~2 days (Note=In 10% FCS) (PubMed=1697930).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Cell type: Follicular cell; CL=CL_0002258.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Conditionally immortalized cell line
Publications

PubMed=1697930; DOI=10.1128/mcb.10.10.5365-5377.1990; PMCID=PMC361234
David Wynford-Thomas, Jane A. Bond, Fiona S. Wyllie, Jorge S. Burns, Edward Dillwyn Williams, Tania A. Jones, Denise Sheer, Nicholas Robert Lemoine;
Conditional immortalization of human thyroid epithelial cells: a tool for analysis of oncogene action.
Mol. Cell. Biol. 10:5365-5377(1990)

Cross-references
Cell line collections (Providers) ECACC; 90011610
Cell line databases/resources CLO; CLO_0008210
CLDB; cl3742
Encyclopedic resources Wikidata; Q54931116
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14