Cellosaurus logo
expasy logo

Cellosaurus NH17 (CVCL_2657)

[Text][XML][JSON]
Cell line name NH17
Accession CVCL_2657
Resource Identification Initiative To cite this cell line use: NH17 (RRID:CVCL_2657)
Comments Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Leu1600Pro (c.4799T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Pro2514Argfs*4 (c.7541_7542delCT); ClinVar=VCV000581973; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000040468; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln214Ter (c.640C>T); ClinVar=VCV000428759; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Heterozygous (from parent cell line).
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0013 (MOLT-4)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
Publications

PubMed=11892817; DOI=10.1002/j.1460-2075.1983.tb01629.x; PMCID=PMC555328
Oscar R. Burrone, Franco Calabi, Richard F. Kefford, Cesar Milstein;
Somatic variants of the level of expression of a cell surface antigen.
EMBO J. 2:1591-1595(1983)

Cross-references
Cell line collections (Providers) ECACC; 92111101
Cell line databases/resources CLO; CLO_0008169
CLDB; cl3698
cancercelllines; CVCL_2657
Encyclopedic resources Wikidata; Q54930508
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22