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CDKN2A/p16 is inactivated in most melanoma cell lines.
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Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.
Int. J. Cancer 75:590-595(1998)

PubMed=10338330; DOI=10.1097/00008390-199902000-00003
Helen Rizos, Artur P. Darmanian, James O. Indsto, Jenniffer A. Shannon, Richard F. Kefford, Graham J. Mann;
Multiple abnormalities of the p16INK4a-pRb regulatory pathway in cultured melanoma cells.
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PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Peter Johansson, Sandra Pavey, Nicholas K. Hayward;
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
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