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Cellosaurus MM415 (CVCL_2608)

[Text version]
Cell line name MM415
Synonyms MM 415
Accession CVCL_2608
Resource Identification Initiative To cite this cell line use: MM415 (RRID:CVCL_2608)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CBA=CBA-1351; DepMap=ACH-001569

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,19
D3S135814,15
D5S81811
D7S8209,11
D8S117914
D13S3179,13
D16S53911
D18S5114,20
D19S43314,15.2
D21S1127,28
FGA23,25
Penta D11,13
Penta E10,12
TH016,9
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=9354451
Marina Castellano, Pamela M. Pollock, Marilyn K. Walters, Louise E. Sparrow, Louise M. Down, Brian G. Gabrielli, Peter G. Parsons, Nicholas K. Hayward;
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Shuraila Francisca Zerp, Andrea van Elsas, Lucy T.C. Peltenburg, Peter I. Schrier;
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Sandra Pavey, Peter Johansson, Leisl Packer, Jennifer Taylor, Mitchell S. Stark, Pamela M. Pollock, Graeme J. Walker, Glen M. Boyle, Ursula Harper, Sarah-Jane Cozzi, Katherine Hansen ...Show all 20 authors... , Laura Yudt, Chris Schmidt, Peter Hersey, Kay Adrian Oswald Ellem, Michael G.E. O'Rourke, Peter G. Parsons, Paul S. Meltzer, Markus Ringner, Nicholas K. Hayward; Show fewer authors
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Mitchell S. Stark, Nicholas K. Hayward;
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Peter Johansson, Sandra Pavey, Nicholas K. Hayward;
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

Cross-references
Cell line collections (Providers) CBA; CBA-1351
ECACC; 10092319
Cell line databases/resources cancercelllines; CVCL_2608
Cell_Model_Passport; SIDM01907
DepMap; ACH-001569
Biological sample resources BioSample; SAMN07624429
Encyclopedic resources Wikidata; Q54906126
Experimental variables resources EFO; EFO_0022368
Gene expression databases GEO; GSM162933
GEO; GSM226671
Polymorphism and mutation databases Cosmic; 889021
Cosmic; 928751
Cosmic; 2159439
Progenetix; CVCL_2608
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26