Cellosaurus cell line Karpas-384 (CVCL

Cellosaurus Karpas-384 (CVCL_2541)

Cross-references
Cell line name	Karpas-384
Synonyms	Karpas 384; KARPAS 384; KARPAS384
Accession	CVCL_2541
Resource Identification Initiative	To cite this cell line use: Karpas-384 (RRID:CVCL_2541)
Comments	Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Doubling time: ~60 hours (ECACC=06120602). Omics: Genomics; Whole exome sequencing. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (DepMap=ACH-001097).
Disease	Primary cutaneous T-cell non-Hodgkin lymphoma (NCIt: C3467) Primary cutaneous T-cell lymphoma (ORDO: Orphanet_171901)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	48Y
Category	Cancer cell line
Web pages	Provider; Cambridge Enterprise; -; https://www.enterprise.cam.ac.uk/reagents/karpas-384-human-t-cell-non-hodgkins-lymphoma-cell-line/
Publications	PubMed=8391614 Martin John Swinnerton Dyer, Elisabeth Nacheva, Patricia E. Fischer, Julie M. Heward, Wayne B. Labastide, Abraham Karpas; A new human T-cell lymphoma cell line (Karpas 384) of the T-cell receptor gamma/delta lineage with translocation t(7:14) (p13;q11.2). Leukemia 7:1047-1053(1993) PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893 Gail Stranks, Susan E. Height, Paul Mitchell, Dalal Mouneimne Jadayel, Martin A.R. Yuille, Corinne F.M. De Lord, Robyn D. Clutterbuck, Jennie G. Treleaven, Ray Leonard Powles, Elisabeth Nacheva, David G. Oscier ...Show all 17 authors... , Abraham Karpas, Gilbert Marcel Lenoir, Stephen D. Smith, John L. Millar, Daniel Catovsky, Martin John Swinnerton Dyer; Show fewer authors Deletions and rearrangement of CDKN2 in lymphoid malignancy. Blood 85:893-901(1995) DOI=10.1016/B978-0-12-221970-2.50457-5 Hans Gunther Drexler; The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)
Cell line collections (Providers)	ECACC; 06120602
Cell line databases/resources	cancercelllines; CVCL_2541 Cell_Model_Passport; SIDM01737 DepMap; ACH-001097
Encyclopedic resources	Wikidata; Q54899498
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	21